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What's new in atopic eczema? An analysis of systematic reviews published in 2010-11.

Author: FutamuraM, ThomasK S, TorleyD, WilliamsH C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review summarizes key findings from 24 systematic reviews on atopic eczema (AE). Early daycare, endotoxin exposure, unpasteurized milk consumption, and early dog exposure may be protective, while early antibiotic use may increase AE risk. There is no strong evidence for the benefits of exclusive breastfeeding, hydrolysed protein formulas, soy formulas, maternal antigen avoidance, omega-3 or omega-6 fatty-acid supplementation, or prebiotics or probiotics for AE prevention. Proactive treatment with topical anti-inflammatory agents is effective in preventing AE flares. Tacrolimus 0.1% is superior to pimecrolimus for treating AE, and tacrolimus is similar in efficacy to mild/moderate topical corticosteroids. Evidence for the role of education in managing AE is inconclusive. There is no clear evidence for the efficacy of homeopathy, botanical extracts, or Chinese herbal medicine in treating AE.
Paper Details　
Original Abstract of the Article :
This review provides a summary of key findings from 24 systematic reviews of atopic eczema (AE) published or indexed between 1 August 2010 and 31 December 2011, updating published summaries from previous years. Epidemiological evidence points to the protective effects of early daycare, endotoxin exp...See full text at original site
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引用元：
https://doi.org/10.1111/ced.12143

データ提供：米国国立医学図書館（NLM）

Atopic Eczema: A Multifaceted Condition with Complexities

Atopic eczema (AE), or atopic dermatitis, is a chronic inflammatory skin condition that affects millions worldwide. This research provides a comprehensive review of key findings from systematic reviews published between 2010 and 2011, offering a glimpse into the evolving understanding of this multifaceted disorder. The authors delve into the epidemiology of AE, examining factors that may influence its development, such as early daycare, endotoxin exposure, and antibiotic use in early life. They also explore the effectiveness of various treatment approaches, including topical anti-inflammatory agents, tacrolimus, and educational interventions. The study emphasizes the need for further research on the role of education in managing AE, as well as the need for large, well-designed trials to evaluate the efficacy of alternative therapies, such as homeopathy and botanical extracts. The most notable findings include the protective effects of early daycare and endotoxin exposure, the superiority of tacrolimus over pimecrolimus for treatment, and the mixed results of educational interventions.

The Importance of a Multidisciplinary Approach to AE

This review underscores the need for a multidisciplinary approach to AE, integrating insights from epidemiology, clinical trials, and educational interventions. The findings highlight the importance of individualized treatment plans, considering the patient's age, severity of symptoms, and response to therapy. The study also emphasizes the need for further research to evaluate the efficacy of alternative therapies, such as homeopathy and botanical extracts.

A Journey Through the Desert of AE Management

This research is like a journey through the vast desert of AE management, offering a comprehensive overview of the current landscape. It highlights the importance of early intervention, personalized treatment plans, and the need for further research to develop even better approaches. For individuals struggling with AE, this review provides valuable information and encourages them to consult with a dermatologist or allergist to discuss appropriate treatment options.

Dr.Camel's Conclusion

Atopic eczema is a complex condition that requires a multifaceted approach. This review provides a valuable overview of the current understanding of AE, highlighting the importance of early intervention, personalized treatment plans, and the need for further research to develop better therapeutic options. It reminds us that understanding the complexities of AE is crucial for providing effective care and improving the quality of life for those affected by this common condition.

Date :
  1. Date Completed 2013-10-21
  2. Date Revised 2022-01-29
Further Info :

Pubmed ID

23750610

DOI: Digital Object Identifier

10.1111/ced.12143

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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