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The diagnosis and treatment of giant cell arteritis.

Author: BleyThorsten A, LamprechtPeter, NessThomas, SchmidtWolfgang A

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Giant cell arteritis, if untreated, progresses to involve the aorta and its collateral branches, leading to various complications. Late diagnosis and treatment can have serious consequences, including irreversible loss of visual function.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Giant cell arteritis (GCA) is the most common systemic vasculitis in persons aged 50 and above (incidence, 3.5 per 100,000 per year). It affects cranial arteries, the aorta, and arteries elsewhere in the body, e.g., in the limbs. METHODS: We selectively review the pertinent literature, ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679627/

データ提供：米国国立医学図書館（NLM）

Giant Cell Arteritis: Diagnosis and Treatment

In the realm of [vasculitis], giant cell arteritis (GCA) stands as a significant challenge. This study delves into the diagnosis and treatment of GCA, a condition that affects arteries throughout the body. The researchers provide a comprehensive overview of the disease, its symptoms, diagnostic methods, and treatment options. It’s like a map leading us through the treacherous terrain of GCA, guiding us towards effective care.

Understanding the Symptoms and Diagnosis of GCA

The study outlines the characteristic symptoms of GCA, including temporal headaches, jaw claudication, scalp tenderness, visual disturbances, and systemic symptoms such as fever and weight loss. It also emphasizes the importance of laboratory testing, imaging studies, and temporal artery biopsy for accurate diagnosis. This is like recognizing the unique signs of a desert storm, enabling us to take appropriate precautions and seek shelter.

Treating GCA with Corticosteroids and Methotrexate

The researchers discuss the standard treatment for GCA, which involves corticosteroids. However, they also highlight the potential for adverse effects associated with long-term corticosteroid use. They recommend methotrexate as a potential alternative to minimize corticosteroid use. This is like finding a more sustainable source of water in the desert, reducing our reliance on temporary, albeit potentially harmful, solutions.

Dr.Camel's Conclusion

This research provides a valuable guide for navigating the desert of GCA. The study highlights the importance of timely diagnosis and treatment to prevent serious complications. It’s like finding a well-stocked caravan, equipped with the knowledge and tools needed to traverse the challenging terrain of GCA.

Date :
  1. Date Completed 2013-12-09
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

23795218

DOI: Digital Object Identifier

PMC3679627

SNS
PICO Info
in preparation
Languages

English

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