Long-term effects on cognitive function of postmenopausal hormone therapy prescribed to women aged 50 to 55 years.

Author: , BrownCandice M, EspelandMark A, GoveasJoseph S, LeBlancErin S, LengIris, LiWenjun, MansonJoAnn E, RappStephen R, ResnickSusan M, RobinsonJennifer, ShumakerSally A, StefanickMarcia L, VaughanLeslie, Wactawski-WendeJean

Paper Details 
Original Abstract of the Article :
IMPORTANCE: Postmenopausal hormone therapy with conjugated equine estrogens (CEEs) may adversely affect older women’s cognitive function. It is not known whether this extends to younger women. OBJECTIVE: To test whether prescribing CEE-based hormone therapy to postmenopausal women aged 50 to 55 yea...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/23797469

データ提供:米国国立医学図書館(NLM)

Hormone Therapy: Navigating the Desert of Cognitive Health

The world of women's health is a complex desert, with scientists constantly seeking to understand the impact of hormone therapy on various aspects of well-being. This study investigates the long-term effects of conjugated equine estrogens (CEEs) on cognitive function in postmenopausal women. The researchers analyzed data from a large, randomized controlled trial, evaluating the cognitive performance of women who had received CEE-based hormone therapy compared to those who received placebo. The study findings suggest that CEE-based hormone therapy, when initiated in younger postmenopausal women, does not have sustained long-term effects on cognitive function, either positive or negative. This research is like a careful camel navigating a vast and challenging desert, seeking to understand the intricate relationship between hormones, aging, and cognitive health.

Hormone Therapy and Cognitive Function: A Balanced Desert Journey

The study's findings highlight the absence of sustained long-term effects of CEE-based hormone therapy on cognitive function in younger postmenopausal women. The researchers found no significant differences in global cognitive function or any specific cognitive domains between the treatment and placebo groups. This research is like a camel caravan traversing a vast desert, maintaining a steady and balanced course, neither experiencing significant gains nor losses along the way.

Navigating the Desert of Menopause

The study underscores the importance of understanding the long-term effects of hormone therapy on cognitive function in postmenopausal women. While the researchers found no sustained effects in younger women, further research is needed to explore the potential impact of hormone therapy on cognitive function in older women or those with specific health conditions. This research is like a guide leading a caravan through a desert, recognizing the need for careful navigation and ongoing observation to ensure safe passage for all.

Dr.Camel's Conclusion

This research provides valuable insights into the long-term effects of CEE-based hormone therapy on cognitive function in younger postmenopausal women. While the study found no sustained impact on cognitive function, further research is needed to explore the potential effects in older women or those with specific health conditions. This research is like a compass in the desert, guiding us towards a better understanding of the complex interactions between hormones, aging, and cognitive health.

Date :
  1. Date Completed 2013-12-10
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

23797469

DOI: Digital Object Identifier

NIHMS465895

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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