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Prevention of postoperative recurrence with azathioprine or infliximab in patients with Crohn's disease: an open-label pilot study.
Author: AndrisaniGianluca, ArmuzziAlessandro, De VitisItalo, FedericoFrancesco, FeliceCarla, GuidiLuisa, MarzoManuela, PapaAlfredo, PuglieseDaniela, RapacciniGian Lodovico
Original Abstract of the Article :
Patients with Crohn's disease (CD) often require surgery over their clinical course. However, endoscopic and clinical recurrence of disease appear respectively in up to 80% and 30% of patients after one year. Thus, a prophylactic treatment is needed to reduce the possibility of recurrence. Both azat...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.crohns.2013.04.020
データ提供:米国国立医学図書館(NLM)
Postoperative Crohn's Disease: Azathioprine vs. Infliximab
Crohn's disease, that inflammatory gut condition, can be a real desert storm, leaving patients battling chronic inflammation. This research delves into the post-operative treatment landscape, aiming to prevent disease recurrence in Crohn's patients. The study compared two medications, azathioprine and infliximab, both of which have shown potential for preventing recurrence, but head-to-head comparisons were lacking. Like a desert explorer seeking the best path through a challenging terrain, the study investigated the efficacy of these medications in preventing endoscopic, histological, and clinical recurrence after one year. This study, like a well-placed oasis, offers valuable insights into the best post-operative treatment options for Crohn's patients.
Preventing Recurrence: Azathioprine and Infliximab
The study found that both azathioprine and infliximab showed promise in preventing post-operative recurrence in Crohn's disease patients. Like two different routes through the desert, both medications provided a measure of protection against disease recurrence. The results, like a clear path in the desert, suggest that both azathioprine and infliximab can be valuable tools for managing Crohn's disease and improving long-term outcomes.
Navigating the Desert of Crohn's Disease
If you're living with Crohn's disease, it's crucial to work closely with your doctor to develop the best treatment plan for your individual needs. This research, like a guidebook for the desert, provides valuable insights into the potential benefits of azathioprine and infliximab in preventing post-operative recurrence. Remember, finding the right treatment approach is like finding a hidden oasis, and it takes time, patience, and collaboration.
Dr. Camel's Conclusion
This research adds to our understanding of Crohn's disease management, particularly in the post-operative setting. The study highlights the potential of both azathioprine and infliximab in preventing disease recurrence, offering a glimmer of hope for patients navigating the challenges of this chronic condition. It's a reminder that the desert of Crohn's disease can be traversed with the right tools and guidance.
Date :
- Date Completed 2014-07-14
- Date Revised 2022-04-08
Further Info :
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