Prevention of postoperative recurrence with azathioprine or infliximab in patients with Crohn's disease: an open-label pilot study.

Author: AndrisaniGianluca, ArmuzziAlessandro, De VitisItalo, FedericoFrancesco, FeliceCarla, GuidiLuisa, MarzoManuela, PapaAlfredo, PuglieseDaniela, RapacciniGian Lodovico

Paper Details 
Original Abstract of the Article :
Patients with Crohn's disease (CD) often require surgery over their clinical course. However, endoscopic and clinical recurrence of disease appear respectively in up to 80% and 30% of patients after one year. Thus, a prophylactic treatment is needed to reduce the possibility of recurrence. Both azat...See full text at original site
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引用元:
https://doi.org/10.1016/j.crohns.2013.04.020

データ提供:米国国立医学図書館(NLM)

Postoperative Crohn's Disease: Azathioprine vs. Infliximab

Crohn's disease, that inflammatory gut condition, can be a real desert storm, leaving patients battling chronic inflammation. This research delves into the post-operative treatment landscape, aiming to prevent disease recurrence in Crohn's patients. The study compared two medications, azathioprine and infliximab, both of which have shown potential for preventing recurrence, but head-to-head comparisons were lacking. Like a desert explorer seeking the best path through a challenging terrain, the study investigated the efficacy of these medications in preventing endoscopic, histological, and clinical recurrence after one year. This study, like a well-placed oasis, offers valuable insights into the best post-operative treatment options for Crohn's patients.

Preventing Recurrence: Azathioprine and Infliximab

The study found that both azathioprine and infliximab showed promise in preventing post-operative recurrence in Crohn's disease patients. Like two different routes through the desert, both medications provided a measure of protection against disease recurrence. The results, like a clear path in the desert, suggest that both azathioprine and infliximab can be valuable tools for managing Crohn's disease and improving long-term outcomes.

Navigating the Desert of Crohn's Disease

If you're living with Crohn's disease, it's crucial to work closely with your doctor to develop the best treatment plan for your individual needs. This research, like a guidebook for the desert, provides valuable insights into the potential benefits of azathioprine and infliximab in preventing post-operative recurrence. Remember, finding the right treatment approach is like finding a hidden oasis, and it takes time, patience, and collaboration.

Dr. Camel's Conclusion

This research adds to our understanding of Crohn's disease management, particularly in the post-operative setting. The study highlights the potential of both azathioprine and infliximab in preventing disease recurrence, offering a glimmer of hope for patients navigating the challenges of this chronic condition. It's a reminder that the desert of Crohn's disease can be traversed with the right tools and guidance.

Date :
  1. Date Completed 2014-07-14
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

23810678

DOI: Digital Object Identifier

10.1016/j.crohns.2013.04.020

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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