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Behavioral effects of bidirectional modulators of brain monoamines reserpine and d-amphetamine in zebrafish.
Author: CollinsChristopher, GebhardtMichael, KalueffAllan V, KyzarEvan, LandsmanSamuel, RobinsonKyle, StewartAdam Michael
Original Abstract of the Article :
Brain monoamines play a key role in the regulation of behavior. Reserpine depletes monoamines, and causes depression and hypoactivity in humans and rodents. In contrast, d-amphetamine increases brain monoamines' levels, and evokes hyperactivity and anxiety. However, the effects of these agents on be...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://pubmed.ncbi.nlm.nih.gov/23827499
データ提供：米国国立医学図書館（NLM）
Zebrafish: A Tiny Desert Oasis for Neuroscience Research
The world of neuroscience is a vast and complex desert, full of intricate pathways and hidden wonders. Researchers are constantly seeking new tools and models to unravel the mysteries of the brain, much like explorers searching for a hidden oasis in a parched landscape. This research explores the potential of zebrafish, a tiny desert creature, as a model organism for studying brain function and drug effects.
The researchers, acting as expert desert guides, utilized zebrafish to study the effects of reserpine and d-amphetamine, two drugs that modulate brain monoamines. They observed that these drugs, like desert mirages, had distinct effects on zebrafish behavior, providing valuable insights into their neurochemical mechanisms.
The study's findings highlight the potential of zebrafish as a promising model for neuroscience research. This tiny desert creature, much like a desert plant adapting to harsh conditions, offers a powerful tool for understanding the complex workings of the brain.
A Miniature Oasis of Knowledge: Zebrafish as a Model Organism
The study's results showcase the remarkable potential of zebrafish as a model organism for neuroscience research. The researchers found that zebrafish exhibited behavioral responses to drugs that closely mirrored those observed in humans and rodents, indicating the value of this tiny creature as a powerful tool for studying brain function.
Exploring the Desert Landscape: Unlocking Brain Mysteries
This research underscores the importance of exploring diverse model organisms in neuroscience research. Zebrafish, with their unique adaptability and genetic similarities to humans, offer a valuable window into the complex world of the brain.
Dr. Camel's Conclusion
In the vast desert of neuroscience, zebrafish stand as a miniature oasis of knowledge, providing a valuable model for studying brain function and drug effects. Their adaptability, genetic similarity to humans, and ease of observation make them a powerful tool for unraveling the mysteries of the brain.
Date :
- Date Completed 2014-03-14
- Date Revised 2021-10-21
Further Info :
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English
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