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Desmopressin administration in children with central diabetes insipidus: a retrospective review.

Author: AmblerGeoffrey R, MaguireAnn M, OoiHooi Leng

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study reviewed the patterns of desmopressin use and side effects in children with central diabetes insipidus, emphasizing the importance of managing water intoxication and hyponatremia.
Paper Details　
Original Abstract of the Article :
Central diabetes insipidus (DI) is a rare disorder in children caused by a deficiency of antidiuretic hormone arginine (vasopressin). Desmopressin is the first line agent in management of central DI. However, one of the side effects of desmopressin is water intoxication and hyponatraemia. This study...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/23843580

データ提供：米国国立医学図書館（NLM）

Navigating Central Diabetes Insipidus in Children: A Camel's Perspective

Central diabetes insipidus (DI), a rare condition characterized by a deficiency of antidiuretic hormone, can lead to excessive thirst and frequent urination. This study reviewed the patterns of desmopressin use and side effects in children with central DI. Desmopressin, a synthetic analog of antidiuretic hormone, is a common treatment for central DI, but it can cause side effects such as water intoxication and hyponatremia. The researchers aimed to better understand the use and risks associated with desmopressin in children with central DI.

Desmopressin: A Double-Edged Sword in Central Diabetes Insipidus

The study found that desmopressin is a widely used treatment for central DI in children, but it can lead to side effects such as water intoxication and hyponatremia. The study's findings highlight the importance of careful monitoring and appropriate dosing of desmopressin to minimize potential complications. It also underscores the need for ongoing research to develop safer and more effective treatment options for central DI.

Managing Central Diabetes Insipidus: What This Means for You

This study provides valuable insights into the management of central DI in children. If your child is diagnosed with central DI, it's crucial to work closely with their doctor to develop a personalized treatment plan. Regular monitoring and adherence to the prescribed treatment regimen are essential for minimizing potential side effects and ensuring the best possible outcome for your child.

Dr. Camel's Conclusion

This study sheds light on the complex challenges of managing central DI in children. The use of desmopressin offers a potential solution, but it's essential to carefully weigh the risks and benefits. Just as a camel must carefully navigate a desert landscape to find water, so too must we carefully manage the treatment of central DI to ensure the health and well-being of our patients.

Date :
  1. Date Completed 2014-07-16
  2. Date Revised 2013-10-31
Further Info :

Pubmed ID

23843580

DOI: Digital Object Identifier

/j/jpem.ahead-of-print/jpem-2013-0078/jpem-2013-0078.xml

Related Literature

Article Analysis
・Side Effects of desmopressin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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