Current place of monoamine oxidase inhibitors in the treatment of depression.

Author: HerrmannNathan, ShulmanKenneth I, WalkerScott E

Paper Details 
Original Abstract of the Article :
This paper reviews the discovery and history of the use of irreversible monoamine oxidase (MAO) inhibitors (MAOIs) such as phenelzine, tranylcypromine and isocarboxazid, as well as the second generation selective and reversible MAOIs such as the MAO-A inhibitor, moclobemide and the MAO-B inhibitor, ...See full text at original site
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引用元:
https://doi.org/10.1007/s40263-013-0097-3

データ提供:米国国立医学図書館(NLM)

Monoamine Oxidase Inhibitors: A Vital Tool for Treating Depression

This research reviews the history and current role of monoamine oxidase inhibitors (MAOIs) in the treatment of depression, a complex mental health condition that can significantly impact quality of life. The study explores the evolution of MAOI use, from the early discovery of irreversible MAOIs to the development of newer, selective, and reversible MAOIs. The researchers discuss the efficacy and safety of MAOIs in treating various forms of depression, including treatment-resistant depression, atypical depression, and bipolar depression. This study aims to provide a comprehensive overview of the current place of MAOIs in the treatment of depression, highlighting their potential benefits and limitations.

MAOIs: An Effective Treatment Option for Specific Forms of Depression

The review highlights the effectiveness of MAOIs in treating challenging forms of depression, particularly those that have not responded to other treatments. However, it also acknowledges the declining use of MAOIs due to concerns about potential drug interactions and dietary restrictions. The researchers emphasize the importance of careful patient selection and monitoring to maximize the benefits of MAOI therapy while minimizing risks.

Navigating Depression Treatment: Understanding the Role of MAOIs

This research underscores the importance of understanding the role of MAOIs in the treatment of depression. Imagine a camel navigating a vast desert, where different routes lead to different destinations. Similarly, different treatment options exist for depression, with MAOIs offering a viable path for certain individuals. This study encourages a comprehensive understanding of the benefits and limitations of MAOIs to facilitate informed decision-making in depression treatment.

Dr.Camel's Conclusion

This review highlights the significant role of MAOIs in the treatment of depression. It’s like a camel discovering a hidden oasis in the desert, offering a valuable resource for individuals who haven't found relief from other treatments. This study emphasizes the importance of understanding the nuances of MAOI therapy and its potential benefits for specific types of depression.

Date :
  1. Date Completed 2014-04-14
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23934742

DOI: Digital Object Identifier

10.1007/s40263-013-0097-3

Related Literature

SNS
PICO Info
in preparation
Languages

English

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