Paper Details

  1. Home
  2. Paper Details

A double-blind placebo-controlled randomized trial of varenicline for smokeless tobacco dependence in India.

Author: GoelzPatricia, GuptaTina, JainRaka, JainVeena, JhanjeeSonali, MittalSwati, SchnollRobert A, WileytoE Paul

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

Varenicline was safe and effective for treating smokeless tobacco dependence in India, with a higher self-reported abstinence rate compared to placebo. Further research is warranted.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: The rate of smokeless tobacco use in India is 20%; its use causes serious health problems, and no trial has assessed behavioral or pharmacological treatments for this public health concern. This trial evaluated varenicline for treating smokeless tobacco dependence in India. METHODS: T...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864491/

データ提供：米国国立医学図書館（NLM）

Varenicline: A Potential Breakthrough in Smokeless Tobacco Dependence Treatment

In the ongoing battle against [tobacco dependence], we're always seeking new and effective therapies. This research explores the potential of [varenicline] in treating [smokeless tobacco dependence] in India. Using [a double-blind placebo-controlled randomized trial], the authors assess the efficacy and safety of varenicline in a population with a high prevalence of smokeless tobacco use.

A Promising New Treatment for Smokeless Tobacco Dependence

The study found that [varenicline was associated with a significant increase in self-reported abstinence rates] compared to placebo. While [biochemically confirmed abstinence rates were not statistically different], varenicline was associated with a [higher likelihood of recovery to abstinence]. These findings suggest that varenicline may be a [promising new treatment option] for smokeless tobacco dependence.

Breaking Free from Tobacco's Grip

This research offers hope for individuals struggling with [smokeless tobacco dependence]. The findings suggest that [varenicline] may be a valuable tool in helping people quit. It's like finding a wellspring of hope in the vast and unforgiving desert of addiction, offering a pathway to a healthier life.

Dr.Camel's Conclusion

This study provides encouraging evidence for the efficacy and safety of varenicline in treating smokeless tobacco dependence in India. The findings highlight the potential of this medication as a valuable tool in helping individuals break free from tobacco's grip. This research is a beacon of hope in the ongoing fight against tobacco addiction, offering a path to a healthier and more fulfilling life.

Date :
  1. Date Completed 2014-09-03
  2. Date Revised 2023-11-04
Further Info :

Pubmed ID

23946326

DOI: Digital Object Identifier

PMC3864491

Related Literature

Article Analysis
・Effective treatment of smokeless tobacco
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.