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Oral, esophageal and cutaneous lichen ruber planus controlled with alitretinoin: case report and review of the literature.

Author: CozzioAntonio, DummerReinhard, FrenchLars E, GublerChristoph, KoliosAntonios G A, Marques MaggioEwerton, NavariniAlexander A

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Oral alitretinoin may be a new, well-tolerated treatment option for esophageal lichen planus (LP) after failed response to conventional treatments.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Therapy-resistant lichen planus (LP) can be a challenging condition for dermatologists. There are some case reports about successful treatments with alitretinoin of cutaneous and oral, but not of esophageal LP. OBJECTIVE: We present the unique case of a patient with cutaneous, oral and ...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.1159/000349980

データ提供：米国国立医学図書館（NLM）

Lichen Planus: A Desert of Skin and Mucosal Discomfort

The world of [dermatology] often presents challenging conditions, and [lichen planus] is a prime example. This research explores the therapeutic potential of [alitretinoin] in managing therapy-resistant lichen planus, including cutaneous, oral, and esophageal manifestations. The authors present a unique case report of a patient who experienced complete resolution of all lesions after treatment with oral alitretinoin.

A Desert Oasis for Lichen Planus

The study suggests that alitretinoin could be a new, well-tolerated treatment option for lichen planus, even in cases that have been refractory to conventional therapies. It's like discovering a hidden oasis in the midst of a challenging desert journey. The authors highlight the rapid and complete resolution of symptoms in the patient they describe, suggesting promising therapeutic potential.

Navigating the Sands of Lichen Planus

This research provides valuable insights for dermatologists seeking effective treatments for lichen planus. It highlights the need for further studies to fully understand the efficacy and safety of alitretinoin in this condition.

Dr. Camel's Conclusion

This case report offers hope for patients struggling with lichen planus, suggesting a potentially effective treatment option that may be particularly helpful in cases resistant to conventional therapies. Further research is crucial to fully understand the role of alitretinoin in managing this complex condition.

Date :
  1. Date Completed 2014-05-28
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

23948733

DOI: Digital Object Identifier

10.1159/000349980

Related Literature

Article Analysis
・Side Effects of alitretinoin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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