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The effect of timolol, betaxolol, and placebo on corneal sensitivity in healthy volunteers.

Author: ClineschmidtC M, HoehH, KulagaS F, TippingR W, VogelR

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Timolol and betaxolol are eye drops that reduce intraocular pressure. This study tested the effect of these drops on corneal sensitivity in 60 healthy volunteers. Timolol significantly decreased corneal sensitivity 1 minute after instillation. Betaxolol significantly reduced corneal sensitivity at every time point up to 10 minutes.
Paper Details　
Original Abstract of the Article :
This study in sixty healthy volunteers investigated the effect of a single drop of either 0.5% timolol ophthalmic solution, 0.5% betaxolol ophthalmic solution, or placebo on corneal sensitivity as measured by the Cochet-Bonnet anesthesiometer. Corneal sensitivity was measured immediately prior to th...See full text at original site
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引用元：
https://doi.org/10.1089/jop.1990.6.85

データ提供：米国国立医学図書館（NLM）

Eye Drops and Corneal Sensitivity

This research explores the effects of eye drops containing timolol and betaxolol, beta-blocker medications commonly used to treat glaucoma, on corneal sensitivity. The researchers studied the impact of these eye drops on corneal sensitivity in healthy volunteers. They found that both timolol and betaxolol significantly reduced corneal sensitivity, highlighting the potential for these medications to affect the eye's ability to detect touch and pain. The study emphasizes the importance of understanding the potential side effects of eye drops and monitoring corneal sensitivity in patients using these medications.

Eye Drops: A Balancing Act

The study's findings highlight the need to balance the benefits of eye drops with their potential side effects. While beta-blockers, such as timolol and betaxolol, are effective in managing glaucoma, they can also reduce corneal sensitivity. This decreased sensitivity can affect the eye's ability to detect touch and pain, potentially leading to injuries. The study emphasizes the importance of careful monitoring and patient education to minimize the risk of these side effects.

Protecting Your Eyes: A Guide to Eye Drops

Eye drops can be a valuable tool for managing eye conditions, but it's important to use them safely and effectively. This research highlights the need to be aware of the potential side effects of eye drops, including decreased corneal sensitivity. It's essential to consult with an eye care professional to discuss the appropriate use of eye drops, as well as potential risks and benefits. By taking a proactive approach to eye health, we can minimize the risk of complications and preserve our vision.

Dr.Camel's Conclusion

This research, like a desert landscape with its intricate details, reveals the complex interplay between eye drops and corneal sensitivity. While eye drops can be beneficial for managing eye conditions, it's important to be aware of their potential side effects. By consulting with an eye care professional and following their recommendations, we can ensure the safe and effective use of eye drops, protecting our precious vision.

Date :
  1. Date Completed 1990-10-11
  2. Date Revised 2019-10-29
Further Info :

Pubmed ID

2394934

DOI: Digital Object Identifier

10.1089/jop.1990.6.85

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・Effects of timolol ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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