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Opioids compared to placebo or other treatments for chronic low-back pain.

Author: AtlasSteven, ChaparroLuis Enrique, DeshpandeAmol, FurlanAndrea D, Mailis-GagnonAngela, TurkDennis C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This Cochrane review assessed the efficacy of opioids in adults with chronic low-back pain (CLBP). There is some evidence for short-term efficacy of opioids compared to placebo, but no placebo-RCTs support the effectiveness and safety of long-term opioid therapy for CLBP.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The use of opioids in the long-term management of chronic low-back pain (CLBP) has increased dramatically. Despite this trend, the benefits and risks of these medications remain unclear. This review is an update of a Cochrane review first published in 2007. OBJECTIVES: To determine the ...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD004959.pub4

データ提供：米国国立医学図書館（NLM）

Opioids for Chronic Low-Back Pain: A Critical Evaluation

Chronic low-back pain (CLBP) is a widespread condition that can significantly impact a person's quality of life. This research reviews the evidence for using opioids to treat CLBP. The researchers conducted a systematic review of 15 randomized controlled trials that compared opioids to placebo or other treatments for CLBP. They aimed to determine the effectiveness and safety of opioids for this condition. The researchers found that opioids were generally more effective than placebo for pain relief, but the evidence for their long-term effectiveness and safety was limited.

Opioids for CLBP: A Cautious Approach

This systematic review suggests that opioids may offer short-term pain relief for CLBP, but more research is needed to understand their long-term effects and potential risks. The researchers emphasize the need for careful consideration of the risks and benefits of opioid therapy and the importance of exploring alternative treatment options. This study underscores the need for more robust and long-term research to guide clinical practice and ensure patient safety.

Understanding CLBP and Seeking Expert Care

If you experience chronic low-back pain, it's essential to consult with a healthcare professional for proper diagnosis and treatment. They can evaluate your condition, discuss various treatment options, and help you develop a personalized management plan. This research highlights the importance of considering a multifaceted approach to CLBP management, including non-pharmacological therapies and alternative pain relief strategies.

Dr. Camel's Conclusion

Imagine CLBP as a persistent desert wind that makes it difficult for a camel caravan to travel. Opioids are like a temporary windbreak, offering some relief from the wind, but they may not be a long-term solution. This research reminds us that treating CLBP requires a careful balance, considering the potential benefits and risks of different approaches. Finding the right combination of strategies, like using a sturdy caravan and finding a sheltered route, can lead to a more comfortable and successful journey through the desert.

Date :
  1. Date Completed 2014-02-06
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

23983011

DOI: Digital Object Identifier

10.1002/14651858.CD004959.pub4

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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