Carboplatin +/- topotecan ophthalmic artery chemosurgery for intraocular retinoblastoma.

Author: AbramsonDavid H, BrodieScott E, DunkelIra J, FrancisJasmine H, GobinY Pierre, JonnaGowtham, MarrBrian P

Paper Details 
Original Abstract of the Article :
Carboplatin administered systemically or periocularly can result in dramatic and prompt regression of retinoblastoma. However, both routes are rarely curative alone and have undesirable side effects. We aimed to assess the efficacy and toxicity of carboplatin +/- topotecan delivered by ophthalmic ar...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749169/

データ提供:米国国立医学図書館(NLM)

Battling Retinoblastoma: Ophthalmic Artery Chemosurgery Offers Hope

The field of ophthalmology tackles the challenge of treating eye cancers, including retinoblastoma, a rare but potentially aggressive tumor. This research explores the efficacy and toxicity of carboplatin and topotecan delivered via ophthalmic artery chemosurgery, a technique that delivers chemotherapy directly to the eye through the ophthalmic artery. The study aims to evaluate the potential of this approach for treating intraocular retinoblastoma, a condition that often requires aggressive treatment.

Ophthalmic Artery Chemosurgery: A Targeted Approach to Retinoblastoma Treatment

The study suggests that ophthalmic artery chemosurgery, using a combination of carboplatin and topotecan, may be an effective treatment for intraocular retinoblastoma. This approach allows for targeted delivery of chemotherapy directly to the tumor, minimizing systemic side effects. Further research is needed to establish the long-term efficacy and safety of this technique.

Understanding Retinoblastoma

Retinoblastoma is a rare but serious eye cancer that can affect children. Early detection and prompt treatment are crucial for maximizing the chances of successful treatment and preserving vision. Consulting an ophthalmologist for any concerns regarding eye health, especially in children, is essential for receiving timely diagnosis and care.

Dr.Camel's Conclusion

Retinoblastoma can feel like a dark shadow creeping across the desert of the eye, but ophthalmic artery chemosurgery offers a ray of light, providing a targeted and potentially curative treatment option. By advancing our understanding of this disease and exploring innovative treatment approaches, we can provide hope and fight for the health of our eyes.

Date :
  1. Date Completed 2014-06-15
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23991112

DOI: Digital Object Identifier

PMC3749169

Related Literature

SNS
PICO Info
in preparation
Languages

English

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