An OA phenotype may obtain major benefit from bone-acting agents.

Author: CastañedaSantos, Herrero-BeaumontGabriel, LargoRaquel, LemsWillem F, Roman-BlasJorge A

Paper Details 
Original Abstract of the Article :
Osteoarthritis (OA) joints display relevant microstructure alterations associated to an increase in remodeling at subchondral bone, which supports its crucial role in OA pathogenesis. Despite this, the treatment of knee OA patients with antiresorptive drugs has given discordant results, suggesting t...See full text at original site
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引用元:
https://doi.org/10.1016/j.semarthrit.2013.07.012

データ提供:米国国立医学図書館(NLM)

Treating Osteoarthritis: A Focus on Bone-Acting Agents

Osteoarthritis (OA), a degenerative joint disease, is like a desert landscape where erosion and wear and tear take their toll. This research explores the potential benefits of bone-acting agents for treating OA, focusing on the role of subchondral bone remodeling in the pathogenesis of the disease. The researchers highlight the importance of targeting subchondral bone remodeling as a therapeutic strategy for OA, suggesting that bone-acting agents could be particularly effective in specific patient subsets. The study calls for further research into the use of bone-acting agents for OA treatment, emphasizing the need for a personalized approach based on patient characteristics.

Bone-Acting Agents: A New Avenue for OA Treatment

The study suggests that bone-acting agents could be a valuable addition to the treatment options for OA, especially for patients with increased subchondral bone remodeling. This approach could potentially improve the outcomes of OA treatment by targeting the underlying biological processes involved in the disease.

Finding Oasis in the Desert of OA

This research is a beacon of hope for individuals living with OA, suggesting that new therapeutic approaches targeting bone remodeling could offer improved treatment options. Like a desert traveler seeking a hidden oasis, researchers are continuously seeking new pathways to combat this debilitating disease.

Dr. Camel's Conclusion

This research is like a camel caravan venturing into a desert with a new compass, exploring the potential benefits of bone-acting agents for treating OA. It highlights the importance of considering subchondral bone remodeling as a target for therapeutic intervention, offering hope for a more effective approach to managing this challenging disease.

Date :
  1. Date Completed 2014-09-30
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24016748

DOI: Digital Object Identifier

10.1016/j.semarthrit.2013.07.012

Related Literature

SNS
PICO Info
in preparation
Languages

English

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