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.008% timolol ophthalmic solution. A minimal-effect dose in a normal volunteer model.
Author: BjornssonT, ClementiR, JonesK, LippaE A, Mottow-LippaL S, NaidoffM A
Original Abstract of the Article :
A double-masked, randomized, placebo-controlled, rising-dose, single-dose study was undertaken to assess the effect of low concentrations of timolol maleate ophthalmic solution (0.008%, 0.025%, 0.08%, and 0.25%) on intraocular pressure and its diurnal variation in healthy, normal volunteers. A singl...See full text at original site
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引用元:
https://doi.org/10.1001/archopht.1990.01070030067030
データ提供:米国国立医学図書館(NLM)
The Subtle Power of Timolol in Eye Pressure Management
The eyes are windows to the soul, and their health is crucial to our overall well-being. Glaucoma, a leading cause of irreversible blindness, is often characterized by elevated intraocular pressure. Timolol, a beta-blocker medication, is commonly used to lower eye pressure. This study aimed to determine the effect of low concentrations of timolol on intraocular pressure in healthy volunteers. The researchers conducted a double-masked, randomized, placebo-controlled study to assess the impact of varying doses of timolol. The results showed that even a minimal dose of timolol (0.008%) produced a significant, albeit subtle, decrease in intraocular pressure. The study demonstrated the efficacy of low-dose timolol in managing eye pressure, offering potential benefits for individuals with glaucoma or other conditions requiring pressure control.
Low-Dose Timolol: A Delicate Approach to Eye Pressure
The study indicates that even a small dose of timolol can have a significant impact on intraocular pressure. This finding has implications for developing more individualized and targeted treatment approaches for patients with eye pressure management needs. It’s like discovering a delicate balance in the desert ecosystem, where even a small change in one element can ripple through the entire system.
Navigating the Terrain of Eye Health
This research highlights the importance of precise dosing and individualized treatment approaches in eye health. It underscores the need for careful monitoring and adjustments to ensure optimal therapeutic effects while minimizing potential side effects. It's like navigating a desert landscape, where each step requires careful consideration and adaptability to ensure successful navigation.
Dr. Camel's Conclusion
This study provides valuable insights into the subtle but significant effects of low-dose timolol on intraocular pressure. The findings suggest that even a minimal dose can effectively lower pressure, offering a potential benefit for patients with glaucoma or other conditions requiring pressure control. This research highlights the importance of individualized treatment approaches and underscores the need for careful monitoring and adjustments in managing eye health, ensuring the preservation of this precious window to the soul.
Date :
- Date Completed 1990-02-14
- Date Revised 2019-07-04
Further Info :
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