ATRA-induced cerebral sinus thrombosis.

Author: Fadhilah MohamadNor, LeeKenneth Rohan, PatelDinesh, SubrayanVisvaraja, WinMaung Maung

Paper Details 
Original Abstract of the Article :
All-trans retinoic acid (ATRA) and Idarubicin are part of the AIDA protocol employed for the treatment of Acute promyelocytic leaukaemia (APML) and has been associated with marked improvement in the prognosis. However, it is known to worsen the haematological picture during the course of induction o...See full text at original site
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引用元:
https://doi.org/10.1007/s11239-013-0988-7

データ提供:米国国立医学図書館(NLM)

Unveiling a Rare Side Effect: Cerebral Sinus Thrombosis and ATRA

Acute promyelocytic leukaemia (APML) is a challenging medical condition, but the AIDA protocol has brought hope to many patients. This protocol includes all-trans retinoic acid (ATRA) and Idarubicin, which have significantly improved patient outcomes. However, like a mirage in the desert, ATRA can sometimes lead to unexpected side effects. This study presents a case of a young woman with APML who developed cerebral sinus thrombosis, a rare complication associated with ATRA therapy. The authors highlight the importance of being vigilant for potential side effects, even when using treatments that have proven to be effective.

The Importance of Vigilance in Treatment

This case report serves as a reminder that even with well-established treatments, there’s always the possibility of unforeseen side effects. It emphasizes the need for careful monitoring and early intervention to address any potential complications.

A Reminder to Stay Alert

When dealing with serious medical conditions, it’s crucial to be aware of the potential side effects of any treatment. This case report demonstrates that even rare complications can have a significant impact on patients’ lives. It underscores the importance of open communication between patients and healthcare providers to ensure safe and effective treatment.

Dr.Camel's Conclusion

While ATRA has been a transformative treatment for APML, this case report reminds us that there is always more to learn about the complex interactions between medications and the human body. This research highlights the importance of ongoing vigilance and research to ensure the safety and efficacy of medical treatments.

Date :
  1. Date Completed 2015-02-12
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24046068

DOI: Digital Object Identifier

10.1007/s11239-013-0988-7

Related Literature

SNS
PICO Info
in preparation
Languages

English

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