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Strength training and testosterone treatment have opposing effects on migration inhibitor factor levels in ageing men.

Author: AndersenM, BrixenK, BruunJ M, ChristensenL L, GlintborgD, HougaardD M, KvorningT, LarsenR, RichelsenB

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study of 54 men with low testosterone levels found that strength training plus placebo was associated with decreased inflammatory activity. Testosterone treatment was associated with increased inflammatory activity.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The beneficial effects of testosterone treatment (TT) are debated. METHODS: Double-blinded, placebo-controlled study of six months TT (gel) in 54 men aged 60-78 with bioavailable testosterone (BioT) <7.3 nmol/L and waist >94 cm randomized to TT (50-100 mg/day, n = 20), placebo (n = 18),...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781991/

データ提供：米国国立医学図書館（NLM）

Opposing Effects of Strength Training and Testosterone Treatment on Migration Inhibitor Factor Levels

This study delves into the complex interplay between aging, testosterone, and inflammatory markers in men. The research, involving 54 men aged 60-78, aimed to investigate the effects of testosterone treatment (TT) and strength training (ST) on levels of migration inhibitor factor (MIF) and other inflammatory markers. This study is a valuable contribution to the growing body of research exploring the potential impact of testosterone and exercise on health and aging, particularly in the context of inflammation.

Strength Training and Testosterone: A Tale of Two Approaches

The study revealed opposing effects of TT and ST on MIF levels. While ST was associated with a decrease in MIF, suggesting a reduction in inflammatory activity, TT led to an increase in MIF levels, indicating a potential increase in inflammation. This finding highlights the importance of considering the potential trade-offs associated with different approaches to managing aging and maintaining health.

Navigating the Aging Process

This research underscores the complex interplay between aging, testosterone, and inflammation. It provides valuable insights into the potential impact of different interventions, such as strength training and testosterone therapy, on inflammatory markers. As we navigate the aging process, it is essential to consult with a healthcare professional to develop a personalized approach that considers individual needs and goals.

Dr.Camel's Conclusion

The journey of aging is a fascinating one, filled with both challenges and opportunities. This study sheds light on the intricate relationship between testosterone, exercise, and inflammation. It reminds us that maintaining health and well-being in our later years requires a holistic approach, considering multiple factors and seeking guidance from qualified healthcare professionals. As we journey through the sands of time, it is essential to embrace a healthy lifestyle and seek out the knowledge and support we need to navigate this unique phase of life.

Date :
  1. Date Completed 2014-06-05
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24089589

DOI: Digital Object Identifier

PMC3781991

SNS
PICO Info
in preparation
Languages

English

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