A next-generation, serum-free, highly purified Vero cell rabies vaccine is safe and as immunogenic as the reference vaccine Verorab® when administered according to a post-exposure regimen in healthy children and adults in China.

Author: Guinet-MorlotFrançoise, HeBin, HuangLirong, LiJia, LiRongcheng, MinutelloMaria, MoZhaojun, PichonSylvie, WangYunpeng, WuXiaohong

Paper Details 
Original Abstract of the Article :
As an evolution of its currently licensed rabies vaccine Verorab(®), Sanofi Pasteur has developed a next-generation, serum-free, highly purified Vero rabies vaccine (PVRV-NG). Through this Phase III clinical trial, we aimed to demonstrate the non-inferiority of PVRV-NG over Verorab when administered...See full text at original site
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引用元:
https://doi.org/10.1016/j.vaccine.2013.10.043

データ提供:米国国立医学図書館(NLM)

Next-Generation Rabies Vaccine: Safety and Immunogenicity

Rabies is a deadly viral disease, and prompt vaccination is crucial for preventing infection. This study evaluates the safety and immunogenicity of a next-generation, serum-free, highly purified Vero rabies vaccine (PVRV-NG), comparing it to the reference vaccine Verorab. The authors conduct a Phase III clinical trial in healthy children and adults in China, providing valuable insights into the safety and efficacy of this new vaccine.

PVRV-NG Shows Promise as a Safe and Effective Rabies Vaccine

The study demonstrates that PVRV-NG is safe and as immunogenic as the reference vaccine Verorab. The research provides strong evidence supporting the use of PVRV-NG as a safe and effective post-exposure prophylaxis for rabies. This finding is particularly relevant for China, where rabies remains a significant public health concern.

Improving Rabies Prevention with PVRV-NG

This study offers hope for improving rabies prevention strategies. The research suggests that PVRV-NG can be a valuable tool for protecting individuals from this deadly disease. This finding is especially important in regions where rabies remains a significant threat.

Dr. Camel's Conclusion

Just like a camel navigating a desert, where encounters with dangerous creatures are always a possibility, individuals need reliable protection. This study evaluates the safety and efficacy of a next-generation rabies vaccine, offering hope for enhanced rabies prevention strategies. The research highlights the importance of developing safe and effective vaccines to protect individuals from this deadly disease.

Date :
  1. Date Completed 2014-06-26
  2. Date Revised 2013-11-19
Further Info :

Pubmed ID

24148575

DOI: Digital Object Identifier

10.1016/j.vaccine.2013.10.043

Related Literature

SNS
PICO Info
in preparation
Languages

English

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