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Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study.

Author: BagatinEdileia, EnokiharaMilvia M S S, GibsonLawrence, GuadanhimLilia R S, MiotHelio A, SanudoAdriana, TalaricoSérgio

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Oral isotretinoin is the only medication that can lead to long-term improvement or even cure severe acne. It has other benefits as well, making it a potential treatment for conditions beyond acne. Retinoic acid is the standard treatment for sun-damaged skin, but it can cause irritation. Isotretinoin has been studied as a possible alternative for sun-damaged skin, although more research is needed.
Paper Details　
Original Abstract of the Article :
Oral isotretinoin (ISO) is the only drug which promotes prolonged remission or cure of severe acne. It also has other properties, supporting its use for non-acne indications. Retinoic acid (RA) is gold standard treatment for photoaging. ISO for photoaging treatment was reported in non-controlled tri...See full text at original site
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引用元：
https://doi.org/10.1111/ijd.12191

データ提供：米国国立医学図書館（NLM）

Photoaging: Comparing Oral Isotretinoin and Topical Retinoic Acid

Photoaging, like the relentless sun beating down on a desert, can leave its mark on the skin. This research compares the effectiveness of oral isotretinoin and topical retinoic acid in treating photoaging. The authors conducted a randomized, comparative study to evaluate the efficacy and safety of these two treatment options. This research provides valuable insights into the treatment options for photoaging, highlighting the potential of oral isotretinoin as an alternative to topical retinoic acid. This research contributes to the understanding of photoaging treatment, offering a comparative analysis of different therapeutic approaches and their potential benefits and risks.

Comparing Treatment Options for Photoaging

This research provides a comparative analysis of oral isotretinoin and topical retinoic acid in treating photoaging. The authors' findings suggest that oral isotretinoin may offer a viable alternative to topical retinoic acid, potentially reducing skin irritation while achieving similar results. It's like choosing the right sunscreen for a desert trek, selecting the most effective and comfortable option for protecting the skin.

Implications for Skin Care

This research highlights the potential of oral isotretinoin as a treatment option for photoaging. The findings suggest that this medication may offer a less irritating alternative to topical retinoic acid, potentially improving patient comfort and compliance. It's like finding a new shade under a desert tree, offering relief from the harsh sun and a more comfortable journey.

Dr. Camel's Conclusion

This research underscores the potential of oral isotretinoin as a treatment option for photoaging. The findings suggest that this medication may offer a viable alternative to topical retinoic acid, potentially reducing skin irritation while achieving similar results. It's like finding a new oasis in the desert, offering a fresh perspective and a path towards healthier skin.

Date :
  1. Date Completed 2014-08-21
  2. Date Revised 2013-12-19
Further Info :

Pubmed ID

24168514

DOI: Digital Object Identifier

10.1111/ijd.12191

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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