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Effects of immediate blood pressure reduction on death and major disability in patients with acute ischemic stroke: the CATIS randomized clinical trial.

Author: , BazzanoLydia A, ChenChung-Shiuan, ChenJing, CuiYong, GaoYanjun, GengDeqin, GuoLibing, HeJiang, JuZhong, LiDong, LiQunwei, LiYongqiu, LiuChangjie, MaDihui, PengHao, PengYanbo, SunYingxian, TongWeijun, WangDali, WangXuemei, XuTan, XuTian, YangGuang, YuanXiaodong, ZhangFengshan, ZhangJintao, ZhangYonghong, ZhaoQi

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

In a randomized clinical trial of 4071 patients with acute ischemic stroke, immediate blood pressure reduction with antihypertensive medications did not reduce the likelihood of death and major disability at 14 days or hospital discharge. The study found that blood pressure reduction was achieved in both groups, but no statistically significant difference in the primary outcome was observed between the treatment and control groups.
Paper Details　
Original Abstract of the Article :
IMPORTANCE: Although the benefit of reducing blood pressure for primary and secondary prevention of stroke has been established, the effect of antihypertensive treatment in patients with acute ischemic stroke is uncertain. OBJECTIVE: To evaluate whether immediate blood pressure reduction in patient...See full text at original site
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引用元：
https://doi.org/10.1001/jama.2013.282543

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2014-03-20
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

24240777

DOI: Digital Object Identifier

10.1001/jama.2013.282543

Related Literature

Article Analysis
・Effective treatment of ischemic stroke
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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