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High throughput identification and quantification of 16 antipsychotics and 8 major metabolites in serum using ultra-high performance liquid chromatography-tandem mass spectrometry.
Author: De DonckerMireille, MaudensKristof E, MorrensManuel, NeelsHugo, PatteetLisbeth, SabbeBernard
Original Abstract of the Article :
BACKGROUND: Therapeutic drug monitoring of antipsychotics is important for optimizing therapy, explaining adverse effects, non-response or poor compliance. We developed a UHPLC-MS/MS method for quantification of 16 commonly used and recently marketed antipsychotics and 8 metabolites in serum. METHO...See full text at original site
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引用元：
https://doi.org/10.1016/j.cca.2013.11.024
データ提供：米国国立医学図書館（NLM）
A High-Throughput Method for Antipsychotic Monitoring
Antipsychotic medications play a crucial role in managing mental health conditions, but finding the right dosage and monitoring their effectiveness can be a complex task. This research presents a new, efficient method for analyzing multiple antipsychotics and their metabolites in blood samples. It's like having a powerful magnifying glass to see the intricate details of antipsychotic levels in the body.
A Faster, More Accurate Way to Monitor Antipsychotics
The study, published in Journal of Chromatography B, describes a method using ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) to quantify 16 antipsychotic drugs and 8 metabolites in serum. The method is fast, accurate, and sensitive, making it an invaluable tool for optimizing antipsychotic treatment and monitoring patient responses. It's like having a high-speed train that delivers accurate information on antipsychotic levels in the body.
Optimizing Antipsychotic Treatment
The use of this new method could significantly impact the management of mental health conditions. The fast and accurate results help healthcare professionals adjust treatment plans, identify potential drug interactions, and monitor treatment effectiveness, ultimately leading to improved patient care. This research provides a valuable tool for navigating the complex landscape of antipsychotic treatment, ensuring patients receive the most effective care possible.
Dr.Camel's Conclusion
This innovative method is like a refreshing oasis in the desert of antipsychotic treatment, offering a faster, more accurate way to monitor drug levels and optimize treatment outcomes. It promises to revolutionize the way we monitor and manage antipsychotic medications, leading to more personalized and effective treatment for those living with mental health conditions. Remember, with proper monitoring and personalized care, we can navigate the vast desert of mental health challenges with greater ease.
Date :
- Date Completed 2014-10-03
- Date Revised 2022-03-21
Further Info :
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