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Bisphosphonates for the prevention and treatment of osteoporosis in patients with rheumatic diseases: a systematic review and meta-analysis.

Author: ChenZhong, FengZhiyun, WangYue, ZengShumei, ZhengZhiyun

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This meta-analysis found that bisphosphonates (BPs) can preserve bone mass and reduce the incidence of vertebral fractures in rheumatic patients, especially those with glucocorticoid consumption. The efficacy of BPs was better for osteoporosis prevention than for treating osteoporosis in rheumatic patients.
Paper Details　
Original Abstract of the Article :
BACKGROUND: While bisphosphonates (BPs) are commonly used in clinical treatment for osteoporosis, their roles on osteoporosis treatment for rheumatic patients remain unclear. We performed a meta-analysis to evaluate the efficacy of BPs on fractures prevention and bone mass preserving in rheumatic pa...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855695/

データ提供：米国国立医学図書館（NLM）

Bisphosphonates: A Boon for Bone Health

Osteoporosis, a condition characterized by weak and brittle bones, is a common concern, especially for individuals with rheumatic diseases. This study, like a diligent explorer charting the terrain of bone health, systematically reviews the efficacy of bisphosphonates (BPs) in preventing and treating osteoporosis in patients with rheumatic diseases. The research employs a meta-analysis, a powerful technique that combines data from multiple studies, providing a comprehensive assessment of BPs' effectiveness in this specific patient population.

Stronger Bones, Fewer Fractures

The study reveals that BPs are highly effective in preserving bone mass and reducing the incidence of vertebral fractures in rheumatic patients. The research also found that BPs are particularly effective in preventing osteoporosis in rheumatic patients, showing greater benefits compared to treating existing osteoporosis. These findings, like a sturdy camel carrying a heavy load, demonstrate the potential of BPs to strengthen bones and reduce fracture risks in patients with rheumatic diseases.

Taking Care of Bones

This study underscores the importance of proactive bone health management, especially for individuals with rheumatic diseases. The research highlights the potential benefits of BPs in preventing and treating osteoporosis, emphasizing the importance of early intervention and close monitoring to ensure optimal bone health and reduce the risk of fractures.

Dr. Camel's Conclusion

The skeletal system, like the backbone of a camel, provides essential support and structure. This study, like a desert guide leading us to a hidden oasis of bone health, explores the benefits of bisphosphonates in managing osteoporosis. The research highlights the effectiveness of BPs in preventing and treating osteoporosis, especially in individuals with rheumatic diseases, offering valuable insights for maintaining healthy bones and reducing the risk of fractures.

Date :
  1. Date Completed 2014-09-08
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24324644

DOI: Digital Object Identifier

PMC3855695

Related Literature

Article Analysis
・Effective treatment of osteoporosis
SNS
PICO Info
in preparation
Languages

English

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