Hematologic depression following therapy with strontium-89 chloride.

Author: ChiltonH M, CooperM R, CowanR J, FerreeC R, RobinsonR G, WatsonE E

Paper Details 
Original Abstract of the Article :
Initial clinical trials using strontium-89 (Sr-89) chloride for the treatment of painful skeletal metastases have observed minimal or no hematological depression secondary to the radiostrontium. A patient with marked bone marrow depression temporally related to the administration of the Sr-89 is rep...See full text at original site
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引用元:
https://doi.org/10.1097/00003072-198612000-00010

データ提供:米国国立医学図書館(NLM)

Hematologic Depression After Strontium-89 Chloride Therapy

Strontium-89 chloride is a medicine used to treat painful skeletal metastases, which are cancer cells that have spread to the bones. While it's often effective, some patients may experience a side effect called hematologic depression, which means their bone marrow is not producing enough blood cells. This study highlights a case where a patient developed severe bone marrow suppression after treatment with strontium-89 chloride. This is a critical finding, akin to discovering a hidden sandstorm in a seemingly safe desert. The study emphasizes the importance of closely monitoring blood cell counts in patients receiving this treatment, especially those with pre-existing bone marrow issues. This is like having a watchful eye over a delicate ecosystem in the desert, ensuring its stability and balance.

Understanding the Risks of Strontium-89 Chloride

The study reveals that patients with bone marrow tumor replacement, like a fragile oasis struggling in the face of a encroaching desert, may be more vulnerable to hematologic depression after strontium-89 chloride therapy. These patients require extra caution and careful monitoring. This knowledge, like a well-placed guidepost in the desert, can help physicians make informed decisions about using this treatment.

Navigating the Desert of Cancer Treatment

Navigating the challenging landscape of cancer treatment often involves balancing potential benefits against potential risks. This study provides a valuable reminder of the importance of individualizing treatment plans based on patient characteristics. By closely monitoring blood cell counts and being aware of the potential for hematologic depression, doctors can help patients navigate the desert of cancer treatment with greater safety and effectiveness.

Dr. Camel's Conclusion

This study underscores the importance of carefully monitoring blood cell counts in patients receiving strontium-89 chloride therapy. It also highlights the need for extra caution in patients with pre-existing bone marrow issues, as they are at higher risk of developing hematologic depression. The desert of cancer treatment can be unforgiving, and this study is a vital reminder to tread carefully and be aware of the potential hidden dangers.

Date :
  1. Date Completed 1987-04-09
  2. Date Revised 2019-07-20
Further Info :

Pubmed ID

2434277

DOI: Digital Object Identifier

10.1097/00003072-198612000-00010

Related Literature

SNS
PICO Info
in preparation
Languages

English

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