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Fixed combination of hyaluronic acid and chondroitin-sulphate oral formulation in a randomized double blind, placebo controlled study for the treatment of symptoms in patients with non-erosive gastroesophageal reflux.

Author: CorbascioD, EspositoA, FistettoG, MerighiA, PalmieriB, RottigniV

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

While proton pump inhibitors (PPIs) are a major advancement in treating heartburn (GERD), many patients with GERD without visible inflammation (non-erosive reflux disease) experience only partial relief or need additional medications.
Paper Details　
Original Abstract of the Article :
Proton pump inhibitors (PPIs) are a major breakthrough in the medical management of gastroesophageal reflux disease (GERD). In several patients with non erosive reflux disease symptoms (NERD) the response to PPIs is partial or limited and symptoms relief needs the administration of additional medica...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/24379055

データ提供：米国国立医学図書館（NLM）

Fixed combination of hyaluronic acid and chondroitin-sulphate oral formulation in a randomized double blind, placebo controlled study for the treatment of symptoms in patients with non-erosive gastroesophageal reflux

Gastroesophageal reflux disease (GERD), a common condition characterized by stomach acid backing up into the esophagus, can cause discomfort and pain. This study investigates the potential benefits of a fixed combination of hyaluronic acid and chondroitin-sulphate for managing symptoms in patients with non-erosive GERD. The researchers conducted a randomized double-blind, placebo-controlled study to assess the efficacy and safety of this combination therapy.

A New Approach to Reflux Relief

The study suggests that the fixed combination of hyaluronic acid and chondroitin-sulphate may be a promising treatment option for managing symptoms in patients with non-erosive GERD. The researchers observed significant improvements in symptom scores compared to the placebo group. These findings provide valuable evidence for the potential of this combination therapy as an alternative or adjunct to conventional GERD treatments.

Finding Relief in the Desert of Discomfort

GERD, like a desert sandstorm, can create discomfort and disrupt daily life. This study offers a glimmer of hope, suggesting that a fixed combination of hyaluronic acid and chondroitin-sulphate may provide a safe and effective way to manage symptoms. This research could lead to improved treatment options for patients struggling with GERD.

Dr.Camel's Conclusion

This study, like a caravan navigating the harsh desert terrain, explores new approaches to managing GERD. The findings suggest that a fixed combination of hyaluronic acid and chondroitin-sulphate may offer a safe and effective solution for patients seeking relief from the discomfort of non-erosive GERD.

Date :
  1. Date Completed 2014-03-27
  2. Date Revised 2013-12-31
Further Info :

Pubmed ID

24379055

DOI: Digital Object Identifier

24379055

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in preparation
Languages

English

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