Paper Details 
Original Abstract of the Article :
The objective of the study was to evaluate the effect of continuous therapy with bisoprolol on blood pressure, serum lipids, and HDL-cholesterol over a period of 10 months following an initial 3-month titration and short-term treatment period. The results of the short-term study have been presented ...See full text at original site
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引用元:
https://doi.org/10.1097/00005344-198511001-00024

データ提供:米国国立医学図書館(NLM)

Long-Term Effects of Bisoprolol on Blood Pressure and Lipids

[Essential hypertension], a common condition characterized by elevated blood pressure, is often treated with [beta-blockers] such as [bisoprolol]. This study investigated the long-term effects of [bisoprolol] on [blood pressure, serum lipids, and HDL-cholesterol] in patients with [essential hypertension]. The study design involved a [10-month long-term study] after an initial [3-month titration and short-term treatment period]. The results showed that [bisoprolol] effectively controlled [blood pressure] over the long term, with the majority of patients achieving a [supine diastolic blood pressure] of less than or equal to 90 mm Hg. The study also observed a small, but statistically significant, increase in [serum triglycerides] over the course of the study, while [total cholesterol, LDL-cholesterol, and HDL-cholesterol] remained largely unchanged. This suggests that [bisoprolol] may have a modest impact on [lipid profile] but remains an effective treatment for [essential hypertension]. The side effects were rare and comparable to those typically observed with [beta-blockers].

Understanding the Long-Term Effects of Bisoprolol

The study suggests that [bisoprolol] can effectively control [blood pressure] over an extended period. However, it's important to note the potential for a slight increase in [serum triglycerides] during long-term treatment. While this increase was statistically significant, it was relatively small and did not significantly impact other [lipid levels]. The study underscores the need for ongoing monitoring of [lipid levels] in patients receiving long-term [bisoprolol] therapy.

Maintaining Cardiovascular Health

This research underscores the importance of managing [essential hypertension] to prevent complications. While [bisoprolol] can effectively control [blood pressure], it's crucial to be aware of its potential impact on [lipid profile] and consider [lifestyle modifications] or additional medications to address any changes. This study serves as a reminder that maintaining cardiovascular health requires a comprehensive approach that includes [regular monitoring, medication management, and healthy lifestyle choices].

Dr.Camel's Conclusion

This study demonstrates the effectiveness of [bisoprolol] in controlling [blood pressure] over the long term. While it may slightly affect [lipid levels], [bisoprolol] remains a valuable tool for managing [essential hypertension]. It's important to maintain regular monitoring of [lipid levels] and make necessary adjustments to [lifestyle or medication] to ensure optimal cardiovascular health.

Date :
  1. Date Completed 1987-08-10
  2. Date Revised 2019-07-24
Further Info :

Pubmed ID

2439784

DOI: Digital Object Identifier

10.1097/00005344-198511001-00024

Related Literature

SNS
PICO Info
in preparation
Languages

English

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