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Regression of mature lymphatic vessels in the cornea by photodynamic therapy.

Author: BiY, BockF, BucherF, CursiefenC, GehlsenU, HosD

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study analyzed the possibility of regressing corneal lymphatic vessels by photodynamic therapy (PDT) after intrastromal verteporfin injection.
Paper Details　
Original Abstract of the Article :
Corneal (lymph) angiogenesis is a predominant risk-factor for immune rejection after transplantation. Techniques to regress pre-existing pathological corneal lymphatic vessels prior to transplantation are missing so far. Therefore we analysed the possibility to regress corneal lymphatic vessels by p...See full text at original site
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引用元：
https://doi.org/10.1136/bjophthalmol-2013-303887

データ提供：米国国立医学図書館（NLM）

Photodynamic Therapy: A Light-Based Approach to Regressing Corneal Lymphatic Vessels

The field of [ophthalmology] is constantly searching for new ways to prevent [immune rejection] after corneal transplantation. This study investigates the potential of [photodynamic therapy (PDT)] in regressing [pre-existing corneal lymphatic vessels]. Researchers injected [verteporfin intrastromally] and applied PDT to the corneas of study subjects. They found that [PDT effectively regressed mature lymphatic vessels] in the cornea. The study highlighted [the potential of PDT as a pre-transplantation treatment] for preventing immune rejection.

A New Tool for Preventing Corneal Transplant Rejection

This research suggests that [PDT] could be a valuable tool for preventing immune rejection after corneal transplantation. The study's findings demonstrate [the effectiveness of PDT in regressing pre-existing corneal lymphatic vessels].

Shining a Light on Corneal Transplant Rejection

Corneal transplant rejection is a complex challenge. This study shines a light on a new approach to prevention, demonstrating [the potential of PDT to reduce the risk of rejection].

Dr. Camel's Conclusion

This study highlights the potential of photodynamic therapy as a powerful tool for preventing corneal transplant rejection. The researchers have discovered a new light in the desert of transplantation, offering a beacon of hope for patients seeking a better outcome.

Date :
  1. Date Completed 2014-04-10
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

24414403

DOI: Digital Object Identifier

10.1136/bjophthalmol-2013-303887

Related Literature

Article Analysis
・Effects of verteporfin injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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