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Systematic review, network meta-analysis and economic evaluation of biological therapy for the management of active psoriatic arthritis.

Author: BirdAlex, CawsonMatthew Richard, KnightChris, MitchellStephen Andrew, OrmeMichelle Elaine, SpurdenDean, WildeyHenry

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This economic evaluation found that all four licensed TNF-α inhibitors were significantly more effective than placebo in achieving PsARC response in patients with active PsA. Etanercept was found to be the most cost-effective treatment option.
Paper Details　
Original Abstract of the Article :
BACKGROUND: An updated economic evaluation was conducted to compare the cost-effectiveness of the four tumour necrosis factor (TNF)-α inhibitors adalimumab, etanercept, golimumab and infliximab in active, progressive psoriatic arthritis (PsA) where response to standard treatment has been inadequate....See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903562/

データ提供：米国国立医学図書館（NLM）

The Cost-Effectiveness of Biological Therapy for Psoriatic Arthritis: A Comprehensive Analysis

In the field of [rheumatology], the [cost-effectiveness] of [biological therapies] for the treatment of [psoriatic arthritis (PsA)] is a crucial consideration for [clinicians] and [healthcare systems]. This study offers a [systematic review, network meta-analysis, and economic evaluation] of [four tumor necrosis factor (TNF)-α inhibitors] commonly used for [PsA]. The researchers found that [etanercept] was the [most cost-effective treatment option], providing valuable insights for [optimizing treatment strategies] in this patient population.

Etanercept: A Cost-Effective Option for Psoriatic Arthritis

This comprehensive analysis provides strong evidence for the [cost-effectiveness] of [etanercept] in the [management of active PsA]. The researchers' findings demonstrate that [etanercept] offers [a favorable balance between efficacy and cost], making it a [highly attractive treatment option] for both [patients] and [healthcare systems].

Making Informed Decisions about Psoriatic Arthritis Treatment

This research emphasizes the importance of [considering both clinical efficacy and cost-effectiveness] when making decisions about [PsA treatment]. By understanding the [relative benefits and costs] of different [biological therapies], clinicians can better guide patients towards [the most appropriate and value-driven treatment options].

Dr.Camel's Conclusion

Imagine a desert traveler seeking the most efficient path to reach their destination. Similarly, in the vast landscape of PsA treatment options, clinicians must carefully navigate the path to provide the most cost-effective and effective care for their patients. This research, like a seasoned desert guide leading travelers through the dunes, reveals the cost-effectiveness of etanercept for managing PsA. The findings provide valuable insights for making informed treatment decisions, ensuring that patients receive the best possible care while optimizing the allocation of healthcare resources.
Date :
  1. Date Completed 2014-09-29
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

24444034

DOI: Digital Object Identifier

PMC3903562

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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