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Commercially available topical platelet-derived growth factor as a novel agent to accelerate burn-related wound healing.

Author: FidlerPhilip E, JordanMarion H, MauskarNeil A, MinoMatthew J, MoffattLauren T, PrindezeNick, ShuppJeffrey W, TravisTaryn E

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Topical platelet-derived growth factor (PDGF) was shown to speed up epithelialization of partial-thickness wounds in a porcine model, as evidenced by improved histology, clinical appearance, and vascularity.
Paper Details　
Original Abstract of the Article :
The authors investigated whether the application of platelet-derived growth factor (PDGF) to donor site wounds would speed healing in a porcine model. In a red duroc pig model, three wounds that were 3 inches × 3 inches were created with a dermatome (0.06-inch depth) on one side of two different ani...See full text at original site
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引用元：
https://doi.org/10.1097/BCR.0000000000000013

データ提供：米国国立医学図書館（NLM）

Accelerating Burn Wound Healing: The Potential of Topical PDGF

Burn wounds present a significant challenge for wound healing. This study investigated the potential of topical platelet-derived growth factor (PDGF) to accelerate healing in a porcine model. The researchers compared the healing rates of control wounds to wounds treated with topical PDGF, assessing epithelialization and vascularity.

PDGF: A Catalyst for Burn Wound Healing

The study demonstrated that topical PDGF significantly accelerated the healing process in partial-thickness wounds. The PDGF-treated wounds showed faster epithelialization and a quicker return to pre-wounding vascularity compared to control wounds. These findings suggest that topical PDGF may be a valuable therapeutic agent for accelerating burn wound healing.

Healing with Nature's Help: Harnessing the Power of Growth Factors

This research offers hope for improving burn wound healing by harnessing the body's natural healing mechanisms. Topical PDGF may provide a safer and more effective alternative to traditional treatments, potentially leading to faster recovery and better outcomes for burn patients. Think of it as the desert providing nourishing plants and minerals, helping to accelerate the healing process.

Dr. Camel's Conclusion

This study offers promising evidence for the effectiveness of topical PDGF in accelerating burn wound healing. The findings suggest that PDGF may play a significant role in improving patient outcomes and reducing the long-term impact of burn injuries.

Date :
  1. Date Completed 2015-05-19
  2. Date Revised 2018-03-02
Further Info :

Pubmed ID

24476989

DOI: Digital Object Identifier

10.1097/BCR.0000000000000013

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Languages

English

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