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Intraocular concentration of moxifloxacin after intracameral injection combined with presoaked intraocular lenses.

Author: Ben EliahuShmuel, EzovNatan, KleinmannGuy, LipnitzkiInna, MarcovitzArie L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Implanting moxifloxacin-presoaked hydrophilic acrylic intraocular lenses resulted in high intraocular concentrations of the antibiotic. Longer presoaking times were associated with higher concentrations.
Paper Details　
Original Abstract of the Article :
PURPOSE: To evaluate the impact of intraocular lens (IOL) moxifloxacin presoaking time on the intraocular concentration of moxifloxacin achieved after intracameral moxifloxacin injection. SETTING: Harlan Biotech Israel, Rehovot, Israel. DESIGN: Laboratory study METHODS: Sixty eyes of 30 rabbits w...See full text at original site
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引用元：
https://doi.org/10.1016/j.jcrs.2013.08.062

データ提供：米国国立医学図書館（NLM）

Intraocular Moxifloxacin Concentration: A Study on Presoaked Intraocular Lenses

The human eye is a delicate organ, akin to a desert oasis, requiring careful attention to maintain its health. This study focuses on optimizing the delivery of moxifloxacin, an antibiotic used to prevent infection during cataract surgery. Researchers explore the impact of different presoaking times for intraocular lenses (IOLs) on the concentration of moxifloxacin in the eye. The goal is to find the most effective method for delivering the antibiotic to the eye, ensuring a healthy and clear vision for patients.

Presoaking Times and Intraocular Moxifloxacin Concentration

The results show that presoaking IOLs in moxifloxacin for a longer duration leads to higher antibiotic concentrations in the eye. This finding has significant implications for optimizing the delivery of antibiotics during cataract surgery, potentially reducing the risk of infection. Just as a skilled desert guide navigates the treacherous landscape with precision, this research provides a roadmap for achieving optimal antibiotic delivery within the eye.

Minimizing Infection Risks During Cataract Surgery

This study emphasizes the importance of carefully considering the delivery method and duration of antibiotic treatment during cataract surgery. It provides valuable insights into how to minimize the risk of infection, ensuring a smooth and successful procedure for patients. As with a well-prepared desert caravan, meticulous planning and attention to detail are essential for achieving optimal outcomes in cataract surgery.

Dr.Camel's Conclusion

This study provides valuable information for ophthalmologists regarding the optimal delivery of moxifloxacin during cataract surgery. It shows that longer presoaking times for IOLs can enhance antibiotic concentration and potentially reduce infection risk. This is a testament to the ongoing advancements in ophthalmic surgery, ensuring better outcomes for patients seeking clear vision.
Date :
  1. Date Completed 2014-09-05
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24530021

DOI: Digital Object Identifier

10.1016/j.jcrs.2013.08.062

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in preparation
Languages

English

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