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The drooling reduction intervention trial (DRI): a single blind trial comparing the efficacy of glycopyrronium and hyoscine on drooling in children with neurodisability.

Author: ColverAllan, FairhurstCharlie, LodhRaj, O'HareAnne, ParrJeremy R, PenningtonLindsay, SteenNick, WeldonEmma, WilliamsJane

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Drooling is a common problem in children with neurodevelopmental disorders. This condition can lead to skin breakdown, dehydration, and social embarrassment. This study reviews the efficacy and safety of glycopyrronium and hyoscine, the two most commonly used medications to reduce drooling, to help inform clinical decisions about which medication to use and at what dose.
Paper Details　
Original Abstract of the Article :
Drooling saliva is a common problem in children with neurodevelopmental disorders. The negative consequences of drooling include skin breakdown, dehydration, and damage to clothing and equipment. Children and families often suffer social embarrassment due to drooling. There is no evidence about the ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937527/

データ提供：米国国立医学図書館（NLM）

Glycopyrronium vs. Hyoscine for Drooling in Children with Neurodisability

Drooling is a common problem in children with neurodevelopmental disorders, often leading to social embarrassment, skin irritation, and clothing damage. This study compares the effectiveness of glycopyrronium and hyoscine, two commonly used medications for reducing drooling. It's like exploring two different desert oases, seeking a solution for a common problem faced by families and children.

The researchers conducted a single-blind trial, comparing the efficacy of glycopyrronium and hyoscine in children with neurodisability. They evaluated the reduction in drooling, side effects, and patient acceptability. It's like testing two different types of water sources in the desert, assessing their effectiveness and potential side effects.

Addressing Drooling in Children with Neurodisability

This study provides valuable insights into the management of drooling in children with neurodisability. It's like finding a new tool in a desert traveler's toolkit, offering a solution to a common and often frustrating problem.

Navigating the Challenges of Drooling

This research sheds light on the need for better understanding the treatment options for drooling in children with neurodisability. It's like mapping out a new path through the desert, seeking a more effective and comfortable solution for those who are affected by this condition.

Dr.Camel's Conclusion

This study offers a crucial comparison of two common medications for reducing drooling in children with neurodisability. It's like finding a new oasis in the desert, providing a better understanding of the challenges and potential solutions for managing this condition.

Date :
  1. Date Completed 2014-10-21
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24533890

DOI: Digital Object Identifier

PMC3937527

Related Literature

Article Analysis
・Side Effects of glycopyrrolate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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