Effects of celecoxib on inflammatory markers in bipolar patients undergoing electroconvulsive therapy: a placebo-controlled, double-blind, randomised study.

Author: AbdollahiAlireza, AhmadvandAlireza, AkhondzadehShahin, ArtounianValentin, GhaeliPadideh, KargarMona, MojtahedzadehMojtaba, YousefiAbolghasem

Paper Details 
Original Abstract of the Article :
PRINCIPAL: Electroconvulsive therapy (ECT) is a treatment option for patients with bipolar disorder (BD). Alterations of markers have been reported following ECT. AIM: the aim of the present study was to assess the effect of adjunctive celecoxib on the serum cytokines of patient with BD who were un...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/24554598

データ提供:米国国立医学図書館(NLM)

Celecoxib: A Potential Oasis for Inflammation in Bipolar Disorder

Electroconvulsive therapy (ECT), a powerful tool for treating severe mental illness, can sometimes be accompanied by inflammation. This study, like an intrepid explorer seeking a cure for a desert ailment, investigates the potential benefits of adding celecoxib, an anti-inflammatory drug, to ECT treatment for bipolar disorder.

Celecoxib: A Potential Anti-inflammatory Ally

The study found that celecoxib significantly reduced levels of tumor necrosis factor-alpha (TNF-α), a key inflammatory marker, in patients undergoing ECT. This finding suggests that celecoxib may help to mitigate the inflammatory side effects of ECT, like a cool breeze in the hot desert, providing temporary relief.

Navigating Inflammation in Bipolar Disorder

This study offers valuable insights into the potential benefits of adding celecoxib to ECT treatment for bipolar disorder. It highlights the importance of managing inflammation in this patient population, like carefully navigating a desert landscape to avoid treacherous sandstorms.

Dr. Camel's Conclusion

This study, like a desert oasis offering shade and respite, sheds light on the potential of celecoxib to reduce inflammation associated with ECT in bipolar disorder. While further research is needed to fully explore its role in this context, it represents a promising avenue for improving the overall well-being of patients undergoing ECT.
Date :
  1. Date Completed 2014-09-18
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

24554598

DOI: Digital Object Identifier

smw-13880

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.