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Intravenous nisoldipine in severe congestive heart failure.

Author: ArmstrongP W, FrankelD, KarlinskyS J, MoeG W

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Nisoldipine, a calcium channel blocker, was found to be a potent arterial vasodilator in 10 patients with severe congestive heart failure. Nisoldipine increased cardiac index and decreased systemic vascular resistance in a dose-dependent manner without significantly affecting heart rate or filling pressures. The drug appears to be beneficial in patients with low output cardiac failure.
Paper Details　
Original Abstract of the Article :
The acute hemodynamic effects of intravenous nisoldipine were studied in 10 patients with severe congestive heart failure. Nisoldipine was administered in three consecutive doses (1.5, 3.0, and 6.0 micrograms/kg) at least 150 min apart. Following the first dose, mean arterial pressure declined from ...See full text at original site
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引用元：
https://doi.org/10.1097/00005344-198808000-00006

データ提供：米国国立医学図書館（NLM）

Intravenous Nisoldipine in Severe Congestive Heart Failure

Imagine a camel struggling to traverse a desert, its heart pounding as it tries to navigate difficult terrain. This is like the experience of individuals with severe congestive heart failure, a condition that affects the heart's ability to pump blood effectively. This study investigated the acute hemodynamic effects of intravenous nisoldipine, a calcium channel blocker, in patients with severe congestive heart failure. The authors found that nisoldipine effectively lowered blood pressure and improved heart function in these patients. This suggests that nisoldipine may be a beneficial treatment option for individuals with severe congestive heart failure.

Nisoldipine Shows Promise for Improving Heart Function

This study provides valuable insights into the potential benefits of nisoldipine for treating severe congestive heart failure. The findings suggest that nisoldipine can effectively improve heart function by reducing blood pressure and improving blood flow. This research highlights the potential of nisoldipine as a therapeutic option for individuals with this condition.

Importance of Seeking Medical Expertise

Remember, this study was conducted on a small group of patients with severe congestive heart failure. While promising, more research is needed to fully understand the long-term effects of nisoldipine and its potential for a wider range of patients. It is crucial to consult with a qualified healthcare professional to determine the best treatment options for your specific condition. Just as a camel would seek guidance from an experienced guide in the desert, it's important to rely on the expertise of your doctor for your heart health.

Dr. Camel's Conclusion

This study offers a compelling glimpse into the potential of nisoldipine as a treatment option for severe congestive heart failure. The findings highlight the need for further research to explore the effectiveness and safety of nisoldipine in larger populations and over longer periods. This study reinforces the importance of exploring novel treatment strategies for cardiovascular diseases.

Date :
  1. Date Completed 1988-11-07
  2. Date Revised 2019-07-24
Further Info :

Pubmed ID

2459547

DOI: Digital Object Identifier

10.1097/00005344-198808000-00006

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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