Comparative potency of intravenous penbutolol and propranolol in man.

Author: SapruR P, SharmaP L

Paper Details 
Original Abstract of the Article :
A study on the comparative potency of intravenously administered penbutolol, a new non-selective beta adrenoceptor antagonist, on the resting and post-exercise heart rate and rate-pressure product was carried out in 5 normal human subjects. The effects produced by 0.1, 0.2 and 0.3 mg of penbutolol a...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/24597

データ提供:米国国立医学図書館(NLM)

Comparing Penbutolol and Propranolol: A Race to the Finish Line

In the vast desert of pharmacological research, scientists are constantly searching for new oases of effective and safe treatments. This study, published in 1976, delves into the fascinating world of beta-blockers, a class of drugs that help to tame the wild heart. The researchers compared the potency of two beta-blockers, penbutolol and propranolol, by measuring their effects on heart rate and blood pressure in healthy individuals. They discovered that penbutolol, a new player in the field, was significantly more potent than the established propranolol. This finding, like a shimmering mirage in the desert, offers promising possibilities for future treatments.

Penbutolol: A Powerful Contender

The study demonstrated that penbutolol was 7.90 and 7.66 times more potent than propranolol in lowering heart rate and blood pressure, respectively. This suggests that penbutolol could be a valuable tool for managing heart conditions like hypertension.

Heart Health and Everyday Life

These results highlight the importance of finding effective and safe treatments for cardiovascular disease. While penbutolol shows promise, it is important to remember that every camel needs to be watered differently. The best medication for you will depend on your individual needs and health history. Always consult with a healthcare professional to determine the most suitable course of treatment.

Dr. Camel's Conclusion

This study, like a desert wind, blew a refreshing wave of new information into the field of beta-blockers. Penbutolol emerged as a strong contender, showcasing its potential to provide effective heart rate and blood pressure control. As researchers continue to explore the vast landscape of cardiovascular medications, they are constantly searching for more effective and safer ways to navigate the journey to better heart health.
Date :
  1. Date Completed 1978-05-24
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

24597

DOI: Digital Object Identifier

24597

Related Literature

SNS
PICO Info
in preparation
Languages

English

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