Fluconazole prophylaxis in preterm infants: a multicenter case-controlled analysis of efficacy and safety.

Author: GurkaMatt J, HetheringtonSeth, KapikBarry, KaufmanDavid A, MorrisAmy

Paper Details 
Original Abstract of the Article :
BACKGROUND: Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. METHODS: ...See full text at original site
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引用元:
https://doi.org/10.1016/S0378-3782(14)70026-X

データ提供:米国国立医学図書館(NLM)

Fluconazole Prophylaxis for Preterm Infants: A New Oasis in Neonatal Care

This study delves into the effectiveness and safety of fluconazole prophylaxis in preterm infants, a crucial aspect of neonatal care. The authors conducted a multicenter case-controlled analysis to evaluate the impact of fluconazole prophylaxis on the incidence of invasive Candida infections in infants born prematurely. This research offers valuable insights into the prevention of infectious diseases in this vulnerable population, like finding a hidden oasis in the desert of neonatal complications.

Fluconazole Prophylaxis: A Protective Shield Against Candida Infections

The study demonstrates the efficacy of fluconazole prophylaxis in preventing invasive Candida infections in preterm infants. The incidence of these infections was significantly lower in infants receiving fluconazole prophylaxis compared to those who did not. This finding suggests that fluconazole prophylaxis can play a critical role in protecting preterm infants from serious fungal infections. It's like creating a protective barrier around a fragile oasis in the desert, shielding it from the harsh elements.

Fluconazole Prophylaxis: A Safe and Effective Intervention

The authors also highlight the safety of fluconazole prophylaxis in preterm infants. The study found no significant differences in the incidence of other adverse events between infants receiving prophylaxis and those who did not. This reassuring finding reinforces the value of fluconazole prophylaxis as a safe and effective intervention for preventing invasive Candida infections in this vulnerable population. It's like discovering a safe and reliable water source in the desert, providing vital sustenance without any harmful side effects.

Dr.Camel's Conclusion

This research provides compelling evidence supporting the use of fluconazole prophylaxis in preterm infants to prevent invasive Candida infections. The study highlights the efficacy and safety of this intervention, offering a valuable tool for neonatal care providers. It's like finding a hidden oasis in the desert of neonatal infections, providing a safe and effective means of protecting preterm infants from serious fungal infections and promoting their health and well-being.

Date :
  1. Date Completed 2015-01-30
  2. Date Revised 2014-04-08
Further Info :

Pubmed ID

24709470

DOI: Digital Object Identifier

10.1016/S0378-3782(14)70026-X

Related Literature

SNS
PICO Info
in preparation
Languages

English

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