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Clinical considerations for an effective medical therapy in Wilson's disease.

Author: StremmelWolfgang, WeissKarl Heinz

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Wilson's disease is a copper overload disorder that leads to hepatic and neurologic symptoms. This review discusses the need for standardized treatment options, including the importance of careful biochemical monitoring and symptom assessment using validated rating scales.
Paper Details　
Original Abstract of the Article :
Wilson's disease is an autosomal recessively inherited copper overload disorder that leads to hepatic and/or neurologic symptoms. More than a century after the first description of Wilson's disease, the available medical treatment options have not been standardized. The efficacy of the commonly used...See full text at original site
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引用元：
https://doi.org/10.1111/nyas.12437

データ提供：米国国立医学図書館（NLM）

Wilson's Disease: Navigating the Complexities of Copper Overload

The realm of [genetics] often presents us with challenging medical mysteries. [Wilson's disease], an autosomal recessively inherited copper overload disorder, is one such enigma. This review discusses the clinical considerations for effective medical management of Wilson's disease, highlighting the limitations of current treatment strategies and advocating for a more personalized approach to care. The authors emphasize the importance of carefully assessing biochemical response patterns and quantitatively monitoring symptoms using validated rating scales.

Addressing the Gaps in Treatment: A Call for Personalized Medicine

The review highlights the need for a more individualized approach to managing Wilson's disease. The authors suggest that standardized dosage strategies, addressing changes in copper pools, may improve patient adherence and reduce side effects. They also advocate for a comprehensive approach to monitoring and managing the disease, including a systematic evaluation of biochemical markers and symptom severity.

Empowering Patients: A Holistic Approach to Wilson's Disease Care

This review emphasizes the importance of a holistic approach to managing Wilson's disease. By combining careful monitoring, personalized dosage adjustments, and comprehensive symptom assessment, clinicians can potentially improve patient outcomes and minimize the long-term morbidity associated with this complex disorder. This research underscores the need for continued research and development of new treatment strategies to address the unique challenges presented by Wilson's disease.

Dr.Camel's Conclusion

Just as a camel's ability to adapt to the harsh desert environment is crucial for survival, managing Wilson's disease requires a flexible and personalized approach. This review sheds light on the complexities of this condition, emphasizing the need for a comprehensive and individualized treatment strategy to ensure optimal patient care.

Date :
  1. Date Completed 2014-08-13
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

24754532

DOI: Digital Object Identifier

10.1111/nyas.12437

SNS
PICO Info
in preparation
Languages

English

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