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Safety, tolerability and side effects of human papillomavirus vaccines: a systematic quantitative review.

Author: CobucciRicardo Ney, GiraldoPaulo César, GonçalvesAna Katherine, RodriguesHugo Marcus, de MeloAmanda Gosson

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review of HPV vaccines found that they are generally safe and well-tolerated, with the most common side effects being pain, swelling, and redness at the injection site.
Paper Details　
Original Abstract of the Article :
Recently, many studies have evaluated HPV vaccine safety and adverse effects. Two vaccines have been recently evaluated in randomized controlled trials: the bivalent vaccine for HPV 16 and 18 (Cervarix, GlaxoSmithKline Biologicals, Rixensart, Belgium) and the quadrivalent vaccine for HPV 6, 11, 16, ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425215/

データ提供：米国国立医学図書館（NLM）

Human Papillomavirus (HPV) Vaccines: Safety and Tolerability in the Desert of Research

HPV vaccines have revolutionized the fight against cervical cancer and other HPV-related diseases. However, as with any new medical intervention, concerns about safety and tolerability are paramount. This systematic review meticulously analyzes data from randomized controlled trials to assess the safety profile of two HPV vaccines: the bivalent vaccine for HPV 16 and 18 (Cervarix) and the quadrivalent vaccine for HPV 6, 11, 16, and 18 (Gardasil). The authors compiled data from numerous studies, including thousands of participants, to provide a comprehensive overview of the most common adverse effects associated with these vaccines.

HPV Vaccines: A Safe Haven in the Desert of Disease Prevention

The review found that both HPV vaccines were generally well-tolerated, with the most common side effects being injection-site reactions such as pain, swelling, and redness. These side effects were typically mild and transient, with no serious adverse events reported.

HPV Vaccines: A Beacon of Hope for Cervical Cancer Prevention

The findings of this systematic review provide strong evidence for the safety and tolerability of HPV vaccines. The benefits of HPV vaccination in preventing cervical cancer and other HPV-related diseases far outweigh the risks associated with these vaccines.

Dr.Camel's Conclusion

Imagine a desert landscape with a hidden oasis, symbolizing the potential of HPV vaccines to protect against cervical cancer. This systematic review, like a compass guiding us through the vast desert of research, assures us that HPV vaccines are generally safe and well-tolerated. As a wise camel, I encourage individuals to consider vaccination as a crucial step in safeguarding their health.

Date :
  1. Date Completed 2015-03-31
  2. Date Revised 2022-09-02
Further Info :

Pubmed ID

24780368

DOI: Digital Object Identifier

PMC9425215

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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