Intravenous or local injections of flavoxate in the rostral pontine reticular formation inhibit urinary frequency induced by activation of medial frontal lobe neurons in rats.

Author: AshitomiKatsuhiro, KadekawaKatsumi, NishijimaSaori, SugayaKimio, UedaTomoyuki, YamamotoHideyuki

Paper Details 
Original Abstract of the Article :
The rostral pontine reticular formation has a strong inhibitory effect on micturition by facilitating lumbosacral glycinergic neurons. We assessed the influence of the rostral pontine reticular formation on the micturition reflex after noradrenaline injection in the medial frontal lobe. We also exam...See full text at original site
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引用元:
https://doi.org/10.1016/j.juro.2014.04.092

データ提供:米国国立医学図書館(NLM)

Investigating the Role of Rostral Pontine Reticular Formation in Urinary Frequency

This study delves into the intricate relationship between the brain and bladder control, focusing on the role of the rostral pontine reticular formation (RPRF) in regulating urinary frequency. The researchers explored the influence of the RPRF on the micturition reflex, particularly in response to activation of neurons in the medial frontal lobe. They aimed to uncover the intricate interplay between these brain regions and their impact on bladder function.

RPRF Plays a Crucial Role in Inhibiting Urinary Frequency

The study revealed that the RPRF plays a significant role in inhibiting urinary frequency by facilitating lumbosacral glycinergic neurons. The researchers demonstrated that injections of flavoxate into the RPRF effectively suppressed urinary frequency induced by activation of medial frontal lobe neurons. This finding highlights the crucial role of the RPRF in regulating bladder function and its potential as a target for treating urinary frequency disorders.

Understanding the Brain-Bladder Connection

The intricate connection between the brain and the bladder is a fascinating area of research. This study provides valuable insights into the role of the RPRF in regulating urinary frequency, highlighting its potential as a target for therapeutic interventions. Understanding these complex neural pathways opens up new avenues for addressing urinary frequency disorders and improving the quality of life for patients who struggle with this condition. It's like mapping out a new oasis in the vast desert of bladder control research.

Dr.Camel's Conclusion

This research delves into the intricate pathways of the brain-bladder connection, uncovering the vital role of the rostral pontine reticular formation in regulating urinary frequency. The study's findings offer a deeper understanding of the neural mechanisms involved in bladder control, paving the way for more effective treatment strategies for urinary frequency disorders. It's a testament to the constant exploration and discoveries taking place in the field of neuroscience, where every new finding helps us navigate the vast desert of the human brain.

Date :
  1. Date Completed 2014-12-11
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

24793729

DOI: Digital Object Identifier

10.1016/j.juro.2014.04.092

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