Efficacy of daily low-dose sildenafil for treating interstitial cystitis: results of a randomized, double-blind, placebo-controlled trial--treatment of interstitial cystitis/painful bladder syndrome with low-dose sildenafil.

Author: ChenBicheng, ChenHongde, ChenWei, DaiShengjie, LiChengdi, ShaoFeng, WangFeng, WengZhiliang, YeXue ting, YuZhixian, ZhangYirong, ZhouQi

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy of daily low-dose sildenafil for the treatment of nonulcer interstitial cystitis (IC) in women. PATIENTS AND METHODS: Forty-eight women with a clinical diagnosis of IC from 3 medical centers were randomly assigned to treatment with daily low-dose sildenafil (25 m...See full text at original site
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引用元:
https://doi.org/10.1016/j.urology.2014.02.050

データ提供:米国国立医学図書館(NLM)

A New Oasis in the Desert of Bladder Pain: Sildenafil for Interstitial Cystitis

In the vast and sometimes unforgiving desert of medical research, we're always searching for new oases of hope. This study, like a refreshing spring in the desert, explores the effectiveness of sildenafil, a medication commonly known for its role in erectile dysfunction, in treating interstitial cystitis (IC), a condition that brings discomfort and pain to the bladder like a persistent desert wind. Researchers used a randomized, double-blind, placebo-controlled trial, which is like comparing two groups of travelers in the desert, one with a trusted guide (sildenafil) and the other without (placebo), to see if sildenafil could help navigate the challenges of IC. The study found that sildenafil significantly improved IC symptoms, like a soothing balm on a parched landscape, compared to placebo, offering a potential new path through the desert of IC. This research provides a glimmer of hope for those struggling with this challenging condition, opening up new avenues for treatment.

Navigating the Sands of IC: A New Route with Sildenafil

The results of this study are like a beacon in the desert, guiding us towards a new understanding of IC treatment. The research demonstrated that daily low-dose sildenafil improved symptom scores and urodynamic indices in women with IC. This is significant because it provides a potential new treatment option for a condition that often leaves patients searching for relief. The researchers found that sildenafil improved the bladder's capacity and the urge to urinate, like building a larger oasis and creating a more manageable water source. This discovery is a step forward in the journey to find effective and well-tolerated treatments for IC.

A Sip of Hope in the Desert of IC: Sildenafil's Potential

This research sheds light on a potential new treatment for IC, offering a glimmer of hope for those struggling with this condition. The study suggests that sildenafil may be a valuable tool in managing IC symptoms, like a sip of water in the desert. It's important to note that while the results are promising, further research is needed to understand the long-term effects and potential side effects of sildenafil for IC. As always, it's crucial to consult with a healthcare professional before making any decisions about your treatment plan.

Dr.Camel's Conclusion

This study suggests that sildenafil may be a promising new treatment for interstitial cystitis, offering a potential new oasis in the desert of pain. While more research is needed to fully understand its long-term effects, this discovery offers a glimmer of hope for those struggling with this challenging condition.
Date :
  1. Date Completed 2014-09-01
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

24837447

DOI: Digital Object Identifier

10.1016/j.urology.2014.02.050

Related Literature

SNS
PICO Info
in preparation
Languages

English

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