Paper Details 
Original Abstract of the Article :
Aims/Introduction:  One of the reasons for the poor adherence to α-glucosidase inhibitor (αGI) treatment is the need to take medication three times a day. We hypothesized that the administration of miglitol might be effective for the next meal if the miglitol-induced inhibition of α-glucosidase acti...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014902/

データ提供:米国国立医学図書館(NLM)

The Impact of Miglitol Administration on Postprandial Glucose Excursion

This research explores the potential of miglitol, an α-glucosidase inhibitor, to effectively manage postprandial glucose levels in individuals with impaired glucose tolerance. The study investigated the effect of administering miglitol before or after breakfast on postprandial glucose excursion following lunch, without taking miglitol at lunch. The study aimed to assess whether the inhibition of α-glucosidase activity persists long enough to impact the next meal.

Exploring Strategies for Improved Glucose Management

The study's findings suggest that administering miglitol before or after breakfast can effectively reduce postprandial glucose excursion following lunch, even without taking miglitol at lunch. This finding highlights the potential for optimizing α-glucosidase inhibitor therapy by strategically timing medication administration. Further research is needed to confirm these findings and explore the long-term implications of this approach.

Improving Adherence to Glucose Management Medications

The study's findings may lead to improved adherence to α-glucosidase inhibitor therapy by reducing the frequency of medication intake. The potential for effectively managing postprandial glucose levels by taking medication only once or twice a day could enhance patient compliance and improve glycemic control.

Dr.Camel's Conclusion

Like a skilled desert navigator who plans their route to minimize water consumption, individuals with impaired glucose tolerance often seek strategies to optimize their medication regimen. This research explores the potential of strategically timed α-glucosidase inhibitor therapy, offering a promising avenue for improved glucose management and enhanced patient compliance. The findings suggest that a little planning and foresight can go a long way in navigating the challenges of glucose control.

Date :
  1. Date Completed 2014-05-20
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24843527

DOI: Digital Object Identifier

PMC4014902

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Languages

English

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