Recent trends in pediatric bacterial meningitis in Japan--a country where Haemophilus influenzae type b and Streptococcus pneumoniae conjugated vaccines have just been introduced.

Author: AkitaHironobu, IwataSatoshi, SatoYoshitake, ShinjohMasayoshi, SunakawaKeisuke, TakahashiTakao, YagihashiTatsuhiko

Paper Details 
Original Abstract of the Article :
To investigate the trends in incidence and the characteristics of bacterial meningitis in Japan where Haemophilus influenzae type b (Hib) vaccine and 7-valent pneumococcal conjugated vaccine (PCV7) were introduced in 2008 and 2010, respectively, which was 5-20 years after their introduction in weste...See full text at original site
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引用元:
https://doi.org/10.1016/j.jiac.2014.04.007

データ提供:米国国立医学図書館(NLM)

The Impact of Vaccines on Pediatric Bacterial Meningitis in Japan

This study examines the [impact of vaccination] on the incidence and characteristics of bacterial meningitis in Japan, where Haemophilus influenzae type b (Hib) vaccine and 7-valent pneumococcal conjugated vaccine (PCV7) were introduced relatively recently compared to Western countries. The researchers conducted [a nationwide survey] of pediatric and neonatal bacterial meningitis cases from 2001 to 2012, analyzing epidemiological and clinical data. The study revealed a significant decrease in the incidence of H. influenzae and S. pneumoniae meningitis after the introduction of the respective vaccines. The researchers concluded that earlier introduction of these vaccines could have potentially prevented more cases of bacterial meningitis in Japanese children.

Vaccines: A Beacon of Hope in the Desert of Disease

Imagine a desert where the sun's harsh rays are a constant threat to life. In this analogy, vaccines can be seen as vital oases providing refuge and protection. This study demonstrates the powerful impact of vaccines in preventing bacterial meningitis, a potentially life-threatening infection, particularly among young children. The significant decrease in the incidence of H. influenzae and S. pneumoniae meningitis underscores the importance of timely and widespread vaccination programs.

Staying Vigilant: Protecting Children Against Meningitis

While vaccines have been remarkably effective in reducing the incidence of bacterial meningitis, the study highlights the importance of remaining vigilant. The researchers identified certain risk factors for severe outcomes, including convulsions at onset, low CSF glucose, S. agalactiae etiology, and persistent positive CSF culture. It's crucial for parents and caregivers to be aware of these risk factors and seek prompt medical attention if their child displays any signs of meningitis. Early diagnosis and treatment are crucial for ensuring the best possible outcome.

Dr.Camel's Conclusion

This research provides strong evidence supporting the efficacy of Hib and PCV7 vaccines in preventing bacterial meningitis. The findings emphasize the importance of early vaccine introduction and continued vigilance in monitoring potential risk factors for this potentially life-threatening infection.

Date :
  1. Date Completed 2015-03-30
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

24855913

DOI: Digital Object Identifier

10.1016/j.jiac.2014.04.007

SNS
PICO Info
in preparation
Languages

English

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