Direct oral anticoagulants--pharmacology, drug interactions, and side effects.

Author: DempfleCarl-Erik

Paper Details 
Original Abstract of the Article :
The direct thrombin inhibitor, dabigatran, as well as the direct factor Xa inhibtors rivaroxaban, apixaban, and edoxaban, display pharmacodynamic features quite similar to low-molecular-weight heparins, with a time to peak level of 1-4 hours after oral administration, and a half-life between 5 and 1...See full text at original site
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引用元:
https://doi.org/10.1053/j.seminhematol.2014.03.005

データ提供:米国国立医学図書館(NLM)

Navigating the Landscape of Direct Oral Anticoagulants

The field of anticoagulation therapy has undergone a revolution with the advent of direct oral anticoagulants (DOACs). This review provides a comprehensive overview of the pharmacology, drug interactions, and side effects of these novel agents. Like a camel navigating a diverse desert landscape, DOACs offer a range of options for treating thromboembolic disorders, each with its unique characteristics. This review highlights the similarities and differences between various DOACs, emphasizing the importance of understanding their pharmacokinetic profiles and potential interactions to ensure safe and effective treatment.

DOACs: A New Era of Anticoagulation Therapy

DOACs offer several advantages over traditional anticoagulants, including improved convenience, reduced monitoring requirements, and potentially fewer drug interactions. The study highlights the predictable pharmacokinetics of DOACs, allowing for individualized dosing and a streamlined approach to treatment.

Understanding the Risks and Benefits

As with any medication, DOACs come with potential risks and benefits. This review provides valuable insights into the potential side effects, drug interactions, and monitoring considerations associated with DOACs. By carefully weighing these factors, healthcare professionals can make informed decisions about the appropriate use of DOACs for their patients.

Dr.Camel's Conclusion

DOACs represent a significant advancement in the field of anticoagulation therapy, offering a more convenient and potentially safer alternative to traditional anticoagulants. This review provides a comprehensive understanding of the pharmacology, drug interactions, and side effects of DOACs, enabling healthcare providers to make informed decisions about their use.

Date :
  1. Date Completed 2014-09-30
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

24861792

DOI: Digital Object Identifier

10.1053/j.seminhematol.2014.03.005

Related Literature

SNS
PICO Info
in preparation
Languages

English

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