Disease-associated QT-shortage versus quinine associated QT-prolongation: age dependent ECG-effects in Ghanaian children with severe malaria.

Author: AnsongDaniel, BurchardGerd D, BurhenneJürgen, CramerJakob P, FeldtTorsten, Fischer-HerrJohanna, HillJosephine N, HoffmannSteffi, MehrfarParisa, NguahSamuel B, PelletierDaniel, RoggelinLouise, SylverkenJustice, ThielChristian

Paper Details 
Original Abstract of the Article :
While several anti-malarials are known to affect the electric conduction system of the heart, less is known on the direct effects of Plasmodium falciparum infection. Some earlier studies point to a direct impact of Plasmodium falciparum infection on the electric conduction system of the heart. The a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067506/

データ提供:米国国立医学図書館(NLM)

Heart Rhythms in the Desert of Malaria: A Camel's Perspective

In the world of [tropical medicine], we confront the challenges of infectious diseases, particularly malaria, which poses a significant threat to global health. This research explores the intricate effects of Plasmodium falciparum infection and anti-malarial drugs on the electrical conduction system of the heart, focusing on children with severe malaria. It's like navigating a desert of disease, seeking to understand the complex interactions between infection, medication, and cardiac function.

A Delicate Balance: A Camel's Perspective on Heart Rhythms

The study, a careful exploration of the desert of malaria research, investigated the impact of infection and drug-induced effects on the electrical conduction system of the heart. This is like observing a delicate balance in the desert ecosystem, where subtle changes can have profound consequences. The researchers sought to understand the differences between disease-associated QT shortening and quinine-associated QT prolongation, particularly in relation to age.

Navigating the Desert of Malaria: A Camel's Advice

This research underscores the importance of understanding the cardiac effects of both malaria infection and anti-malarial drugs. It's like having a map to guide us through the desert of malaria treatment, helping us make informed decisions about medication and monitoring. The study encourages further research into the long-term cardiac implications of malaria infection and treatment, particularly in children.

Dr. Camel's Conclusion

This study sheds light on the intricate relationship between malaria infection, anti-malarial drugs, and cardiac function. It's like uncovering a hidden oasis of knowledge in the desert of malaria research, reminding us that even seemingly simple interventions can have complex consequences. This research emphasizes the need for careful monitoring and personalized treatment approaches to manage the cardiac risks associated with malaria.

Date :
  1. Date Completed 2015-01-26
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24902591

DOI: Digital Object Identifier

PMC4067506

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Languages

English

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