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Efficacy and safety of oral budesonide suspension in pediatric patients with eosinophilic esophagitis.
Author: CollinsMargaret H, GuptaSandeep K, VitanzaJoanne M
Original Abstract of the Article :
BACKGROUND & AIMS: No treatment has been approved by the U.S. Food and Drug Administration for eosinophilic esophagitis (EoE). We investigated the efficacy and safety of a new formulation of oral budesonide suspension (OBS), a corticosteroid, in a prospective, placebo-controlled, dose-ranging study....See full text at original site
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引用元:
https://doi.org/10.1016/j.cgh.2014.05.021
データ提供:米国国立医学図書館(NLM)
Budesonide for Eosinophilic Esophagitis: A New Oasis
Eosinophilic esophagitis (EoE) is an inflammatory condition affecting the esophagus, and finding effective treatments has been a challenge. This study investigates the efficacy and safety of a new formulation of oral budesonide suspension (OBS), a corticosteroid, in pediatric patients with EoE. The researchers conducted a prospective, placebo-controlled, dose-ranging study to evaluate the effectiveness of OBS in treating EoE.
The study found that medium-dose and high-dose OBS were significantly more effective than placebo in reducing peak eosinophil counts in the esophagus. While all groups, including the placebo group, experienced significant symptom responses, the study did not show a significant difference in symptom response between OBS and placebo.
Budesonide: A Potential Solution
This study provides evidence that OBS may be a potential treatment option for EoE in children. However, further research is needed to optimize dosing and explore the long-term effects of OBS. It's like discovering a new oasis in the desert of EoE research; OBS could be a promising solution, but further exploration is crucial to confirm its true potential.
Navigating EoE
If your child is experiencing symptoms of EoE, consulting a gastroenterologist is essential. They can diagnose the condition and recommend the most appropriate treatment plan. Remember, managing EoE is like navigating a desert landscape; it requires patience, perseverance, and a collaborative approach with healthcare professionals.
Dr.Camel's Conclusion
This study highlights the ongoing search for effective treatments for EoE. The discovery of OBS as a potential treatment option is a step forward in the desert of EoE research. Further research is crucial to understand the full potential of OBS and develop optimal treatment strategies for this challenging condition.
Date :
- Date Completed 2015-08-04
- Date Revised 2022-03-17
Further Info :
Related Literature
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