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Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis.

Author: FordAlexander C, LacyBrian E, LemboAnthony J, MoayyediPaul, QuigleyEamonn M M, SaitoYuri A, SchillerLawrence R, SofferEdy E, SpiegelBrennan M R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Antidepressants and some psychological therapies are effective treatments for irritable bowel syndrome (IBS). The overall summary estimates of treatment effect have remained remarkably stable in the intervening 5 years since the last meta-analysis.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder. Evidence relating to the treatment of this condition with antidepressants and psychological therapies continues to accumulate. METHODS: We performed an updated systematic review and meta-analysis of random...See full text at original site
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引用元：
https://doi.org/10.1038/ajg.2014.148

データ提供：米国国立医学図書館（NLM）

Antidepressants and Psychological Therapies for Irritable Bowel Syndrome: A Meta-Analysis

This meta-analysis examines the effectiveness of antidepressants and psychological therapies in treating irritable bowel syndrome (IBS), a chronic functional gastrointestinal disorder. The authors conducted a systematic review of 48 randomized controlled trials (RCTs) that compared antidepressants with placebo or psychological therapies with control therapies. They found that both antidepressants and psychological therapies, including cognitive behavioral therapy (CBT), hypnotherapy, multicomponent psychological therapy, and dynamic psychotherapy, were effective in reducing IBS symptoms. The relative risk (RR) of IBS symptoms not improving with antidepressants versus placebo was 0.67, while the RR for psychological therapies was 0.68.

The Promise of Effective Treatment for IBS

The findings suggest that both pharmacological and psychological interventions can be beneficial for individuals with IBS. The study provides strong evidence supporting the use of antidepressants and specific psychological therapies in the management of this challenging condition.

Seeking Relief for IBS: Exploring Treatment Options

If you are struggling with IBS, it's essential to consult with a healthcare professional. This research suggests that effective treatment options are available, and a personalized approach that incorporates both pharmacological and psychological interventions may be the most beneficial strategy for managing your symptoms.

Dr.Camel's Conclusion

Just as a camel navigates the unpredictable desert terrain, individuals with IBS often face a challenging journey with their symptoms. This study offers a beacon of hope, highlighting the effectiveness of different treatment approaches, providing a roadmap towards relief for those seeking solace from IBS.

Date :
  1. Date Completed 2014-10-30
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

24935275

DOI: Digital Object Identifier

10.1038/ajg.2014.148

Related Literature

Article Analysis
・Effective treatment of irritable bowel syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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