Ciprofloxacin and probiotic Escherichia coli Nissle add-on treatment in active ulcerative colitis: a double-blind randomized placebo controlled clinical trial.

Author: HalkjærSofie Ingdam, KrogfeltKaren Angeliki, MirsepasiHengameh, MortensenEsben Munk, Nordgaard-LassenInge, PetersenAndreas Munk

Paper Details 
Original Abstract of the Article :
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. The probiotic bacterium Escherichia coli Nissle 1917 (EcN) has been used to maintain and induce clinical remission in UC. Our aim was to test the effect of Ciprofloxacin and/or orally administered EcN as add-on to conventional therapie...See full text at original site
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引用元:
https://doi.org/10.1016/j.crohns.2014.06.001

データ提供:米国国立医学図書館(NLM)

Ciprofloxacin and Probiotic E. coli Nissle: A New Oasis in the Desert of Ulcerative Colitis Treatment?

We're venturing into the often-difficult terrain of ulcerative colitis (UC), a chronic inflammatory bowel disease that can significantly impact quality of life. This double-blind, randomized, placebo-controlled clinical trial, like a team of researchers conducting a meticulous experiment in the desert, investigated the potential benefits of combining ciprofloxacin, an antibiotic, with probiotic Escherichia coli Nissle 1917 (EcN), as an add-on therapy for active UC.

Ciprofloxacin and EcN: A Potential Oasis in the Desert of UC Treatment?

The researchers sought to determine if this combined approach, like finding a hidden oasis with a unique blend of resources, could offer additional benefits for patients with active UC. While the results were promising, the study emphasized the need for further research to confirm the effectiveness and optimize the use of this combined therapy.

Navigating the Desert of UC Treatment with Innovative Approaches

This research, like a map revealing a new path, highlights the ongoing search for effective and safe treatments for UC. The study underscores the importance of exploring innovative approaches, such as combining antibiotics and probiotics, to provide relief from the symptoms of UC and improve patient outcomes.

Dr.Camel's Conclusion

The desert of UC treatment can be a challenging journey, but this research offers a glimmer of hope. Combining ciprofloxacin and EcN, like finding a new oasis in the desert, may hold promise for improving outcomes for patients with active UC. Further research is crucial to refine this approach and ensure its effectiveness and safety. As we continue our exploration through the desert of UC treatment, innovation and perseverance remain essential.

Date :
  1. Date Completed 2015-08-31
  2. Date Revised 2016-10-20
Further Info :

Pubmed ID

24972748

DOI: Digital Object Identifier

10.1016/j.crohns.2014.06.001

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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