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[A combination of nifedipine and diltiazem in the treatment of refractory spastic angina].

Author: BonnetJ L, BoryM, CoutelenN, JolyP

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Diltiazem (D) and nifedipine (N) were studied in combination for spastic angina. While both drugs were effective alone, combined treatment with half doses provided greater protection against coronary spasm compared to monotherapy. This approach offers potential for treating spastic angina while reducing side effects.
Paper Details　
Original Abstract of the Article :
Both diltiazem (D) and nifedipine (N) have been shown to be effective in the treatment of spastic angina, but they sometimes prove inadequate, even in high doses. These two drugs have been given in combination on the grounds of a possible synergistic action, but the results obtained were limited by ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2500912

データ提供：米国国立医学図書館（NLM）

Spastic Angina: A Desert Storm of Chest Pain

Spastic angina, a painful condition affecting the heart, is like a desert storm that suddenly and unexpectedly sweeps across the landscape. This research investigated the effectiveness of a combination of nifedipine and diltiazem in treating patients with refractory spastic angina, those who do not respond well to conventional treatments. The researchers studied the effects of these medications in a group of patients with normal or subnormal coronary vessels, and they found that a combination of nifedipine and diltiazem, administered in half doses, was effective in preventing coronary spasms.

Finding Shelter from the Storm

The study found that the combination of nifedipine and diltiazem, given in half doses, was effective in reducing the severity and frequency of spastic angina episodes. This finding is like finding a safe haven during a desert storm, offering protection from the relentless forces of pain.

Protecting Your Heart's Oasis

Spastic angina is a potentially serious condition that can disrupt your quality of life. This research provides evidence for the potential benefits of a combination of medications in treating refractory cases. Remember, like a camel seeking a safe oasis, it is essential to work closely with your healthcare provider to manage this condition effectively.

Dr. Camel's Conclusion

This research highlights the potential of a combination of nifedipine and diltiazem in treating refractory spastic angina. Like a camel navigating a desert storm, finding the right treatment approach can be a journey. Always consult with a healthcare professional to create a personalized plan for managing your heart health.

Date :
  1. Date Completed 1989-07-31
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

2500912

DOI: Digital Object Identifier

2500912

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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