Paper Details

  1. Home
  2. Paper Details

Nalbuphine for postoperative pain treatment in children.

Author: Pogatzki-ZahnEsther, ReichlSylvia U, SchnabelAlexander, ZahnPeter K

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review discusses the potential use of nalbuphine, a kappa-receptor agonist and µ-receptor antagonist, for postoperative pain management in children. Nalbuphine's efficacy is believed to be similar to morphine, but with a lower risk of opioid-induced side effects and severe adverse events due to its µ-receptor antagonistic properties. However, its exact efficacy, particularly compared to other commonly used opioids, needs further investigation.
Paper Details　
Original Abstract of the Article :
Several surveys over the past few years have demonstrated that postoperative pain in children is not treated appropriately. One pharmacological treatment option in a multimodal approach for postoperative pain treatment is the systemic administration of opioids. However, opioids are rarely used for p...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403789/

データ提供：米国国立医学図書館（NLM）

Nalbuphine for Postoperative Pain in Children: A Promising Option

Postoperative pain in children is often undertreated, and opioids are rarely used due to concerns about adverse events. This study explores the potential of nalbuphine, a kappa-receptor agonist and µ-receptor antagonist, for postoperative pain management in children. Nalbuphine has a similar efficacy to morphine but may have a lower risk of opioid-induced side effects. However, the exact efficacy of nalbuphine in children compared to other opioids remains to be determined.

Navigating the Challenges of Pediatric Pain Management

This study delves into the complex world of pediatric pain management, seeking to address the lack of appropriate treatment options for children experiencing postoperative pain. The research explores the potential of nalbuphine, a lesser-known opioid, as a potential solution for managing this common challenge. The study's findings offer a glimmer of hope for finding safe and effective pain relief options for young patients.

The Importance of Tailored Treatment Approaches

This study emphasizes the importance of tailoring treatment approaches to meet the unique needs of pediatric patients. The research highlights the need for more research to clarify the optimal use of nalbuphine in children and compare its effectiveness to other commonly used opioids. Just as a camel adapts its gait to navigate different desert terrains, healthcare providers must tailor their treatment strategies to address the individual needs of children experiencing postoperative pain.

Dr.Camel's Conclusion

This research offers a promising avenue for improving postoperative pain management in children. The study's findings suggest that nalbuphine, a kappa-receptor agonist and µ-receptor antagonist, could be a valuable addition to the pediatric pain management toolkit. By conducting further research to determine the optimal use of nalbuphine in children and comparing its efficacy to other opioids, we can pave the way for safer and more effective pain relief options for young patients. Just as a camel navigates the harsh desert landscape with resilience and adaptability, we can navigate the complexities of pediatric pain management by embracing innovation and tailoring our approaches to meet the unique needs of our youngest patients.
Date :
  1. Date Completed 2015-01-12
  2. Date Revised 2023-08-07
Further Info :

Pubmed ID

25079857

DOI: Digital Object Identifier

PMC10403789

Related Literature

Article Analysis
・Side Effects of meperidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.