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[Enteric-coated aspirin does not reduce the risk of gastrointestinal side effects].

Author: HaastrupPeter, JarbølDorte Ejg

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review examined the existing literature on the effects of enteric-coating on the incidence of gastrointestinal side effects associated with aspirin. While enteric-coated aspirin was found to cause significantly less minor gastrointestinal lesions compared to plain aspirin after short-term treatment, there was no significant difference in dyspepsia or clinically relevant gastrointestinal bleeding. Therefore, the review concludes that enteric-coated aspirin is not superior to plain aspirin.
Paper Details　
Original Abstract of the Article :
Enteric-coated aspirin has been developed in order to decrease the risk of gastrointestinal side effects. When reviewing the existing literature on the effects of the coating on the incidence of gastrointestinal side effects we find that enteric-coated aspirin causes significantly less minor gastroi...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/25096559

データ提供：米国国立医学図書館（NLM）

Enteric-Coated Aspirin: A Reassessment of Gastrointestinal Side Effects

This study examines the effectiveness of enteric-coated aspirin in reducing gastrointestinal side effects compared to plain aspirin. The researchers reviewed existing literature on the topic, comparing the incidence of gastrointestinal lesions, dyspepsia, and gastrointestinal bleeding. They found that while enteric-coated aspirin reduced minor gastrointestinal lesions, it did not appear to significantly decrease the incidence of dyspepsia or clinically relevant gastrointestinal bleeding.

Debunking the Myth: Enteric-Coated Aspirin and Gastrointestinal Protection

This study challenges the common belief that enteric-coated aspirin offers superior protection against gastrointestinal side effects. The researchers' findings suggest that while enteric-coating may reduce minor lesions, it does not necessarily prevent more clinically relevant gastrointestinal complications. This information is crucial for understanding the potential benefits and limitations of enteric-coated aspirin for patients at risk of gastrointestinal complications.

Implications for Aspirin Use and Patient Safety

The study's findings provide valuable insights for clinicians and patients regarding the use of enteric-coated aspirin. The researchers' findings emphasize the need for careful consideration of individual risk factors and potential complications when prescribing aspirin, regardless of its coating. Further research is warranted to clarify the long-term effects of enteric-coating and its true impact on gastrointestinal health.

Dr. Camel's Conclusion

This study reminds us that even in the desert of pharmaceutical innovation, some myths persist. The research reveals that enteric-coated aspirin, while seemingly offering protection, may not be the complete solution for gastrointestinal concerns. It's important to approach drug choices with a discerning eye, considering the nuanced realities of their effects.

Date :
  1. Date Completed 2017-12-15
  2. Date Revised 2017-12-15
Further Info :

Pubmed ID

25096559

DOI: Digital Object Identifier

V09130544

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