[Incidence, management and costs of adverse effects in chronic hepatitis C patients on triple therapy with telaprevir or boceprevir: first 12 weeks of treatment].

Author: Climente-MartíMónica, Guglieri-LópezBeatriz, Gómez-ÁlvarezSandra, Ventura-CerdáJosé Manuel

Paper Details 
Original Abstract of the Article :
INTRODUCTION: The aim of the study was to analyze the incidence, management and cost associated to hematological and dermatological adverse effects (AE) in chronic hepatitis C patients on triple therapy (TT) with telaprevir (TVR) or boceprevir (BOC). METHODS: An analysis was made on the data record...See full text at original site
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引用元:
https://doi.org/10.1016/j.eimc.2014.05.012

データ提供:米国国立医学図書館(NLM)

Adverse Effects of Triple Therapy for Chronic Hepatitis C: Incidence, Management, and Costs

This study analyzes the incidence, management, and costs associated with hematological and dermatological adverse effects (AEs) in chronic hepatitis C patients receiving triple therapy with telaprevir (TVR) or boceprevir (BOC). The study found that thrombocytopenia and neutropenia were the most common AEs in both treatment groups. Eleven patients required treatment discontinuation, primarily due to toxicity. The study also examined the costs associated with managing AEs, finding that patients with grade III-IV toxicity required more supportive care and incurred higher costs compared to patients with grade I-II toxicity.

Triple Therapy: A Balancing Act Between Benefits and Risks

The study's findings highlight the need for careful monitoring and management of AEs associated with triple therapy for chronic hepatitis C. While triple therapy offers significant potential benefits, it's important to be aware of the potential risks and to weigh the benefits and risks carefully when making treatment decisions.

Navigating Chronic Hepatitis C: A Journey Through Challenging Terrain

The desert landscape, with its changing conditions, can be challenging to navigate. Similarly, navigating chronic hepatitis C can be a difficult journey. This study underscores the importance of considering the potential risks and costs associated with triple therapy, while remaining optimistic about the potential benefits it offers for many patients.

Dr. Camel's Conclusion

This study highlights the complex interplay between medications, adverse effects, and the cost of treatment. It emphasizes the importance of a multi-disciplinary approach to patient care, ensuring that patients receive appropriate monitoring, supportive care, and cost-effective treatment strategies. As we continue to learn more about the treatment of chronic hepatitis C, research like this is vital for guiding clinical practice and improving patient outcomes.
Date :
  1. Date Completed 2017-04-18
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25128462

DOI: Digital Object Identifier

10.1016/j.eimc.2014.05.012

SNS
PICO Info
in preparation
Languages

Spanish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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