[Comparison of low-dose thalidomide and prednisone combined with or without danazol for the treatment of primary myelofibrosis-associated anemia].

Author: FangLiwei, HuNaibo, LiBing, PanLijuan, QinTiejun, QuShiqiang, XiaoZhijian, XuJunqing, XuZefeng, ZhangHongli, ZhangYue

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To observe the clinical effects of low-dose thalidomide (THAL) and prednisone (PRED) with or without danazol (DANA) in patients with primary myelofibrosis (PMF) associated anemia. METHODS: A cohort of 58 PMF patients with anemia (Hb<100 g/L) were retrospectively studied. Of them, 28 pati...See full text at original site
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引用元:
https://doi.org/10.3760/cma.j.issn.0253-2727.2014.08.006

データ提供:米国国立医学図書館(NLM)

Thalidomide, Prednisone, and Danazol: A Trio of Hope for Primary Myelofibrosis-Associated Anemia

The search for effective treatments for [primary myelofibrosis (PMF)]-associated anemia is a continuous journey, and researchers are constantly exploring new therapeutic strategies. This research investigates the clinical effects of [thalidomide], [prednisone], and [danazol] in patients with PMF-associated anemia. The authors embarked on a retrospective study to evaluate the efficacy and safety of these medications in managing the anemia associated with PMF.

A Promising Oasis: Thalidomide, Prednisone, and Danazol in PMF

The study found that a combination of low-dose thalidomide and prednisone, with or without danazol, was effective in treating PMF-associated anemia. The results suggest that these medications could offer a potential oasis for patients struggling with this challenging condition. The study observed a significant hematological response in a substantial portion of the patients, with the combination of thalidomide, prednisone, and danazol showing a longer median response duration. These findings suggest that this therapeutic combination could be a valuable tool for managing PMF-associated anemia, offering a path towards improved health and quality of life.

Navigating the Desert of Myelofibrosis: The Importance of Personalized Treatment

This research provides valuable insights into the potential of thalidomide, prednisone, and danazol as a therapeutic regimen for PMF-associated anemia. The study highlights the importance of personalized treatment approaches and the need for further research to optimize treatment strategies for this complex disease. The journey of managing PMF is like navigating a vast and challenging desert, and this research offers a new compass to guide clinicians towards effective treatment options.

Dr.Camel's Conclusion

This research offers a promising glimpse into the potential of thalidomide, prednisone, and danazol as a therapeutic strategy for PMF-associated anemia. The study highlights the importance of personalized treatment approaches and the need for further research to optimize treatment strategies for this complex disease. It's a reminder that even in the vast desert of complex diseases, new discoveries can pave the way towards better health and hope.

Date :
  1. Date Completed 2015-01-05
  2. Date Revised 2014-08-25
Further Info :

Pubmed ID

25152115

DOI: Digital Object Identifier

10.3760/cma.j.issn.0253-2727.2014.08.006

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SNS
PICO Info
in preparation
Languages

Chinese

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