Methotrexate for induction of remission in ulcerative colitis.

Author: ChandeNilesh, MacDonaldJohn K, McDonaldJohn W D, WangYongjun

Paper Details 
Original Abstract of the Article :
Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Corticosteroids and 5-aminosalicylates are the most commonly used therapies. However, many patients require immunosuppressive therapy for steroid-refractory and steroid-dependent disease. Methotrexate is a medication that is effective ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486224/

データ提供:米国国立医学図書館(NLM)

Navigating the Complexities of Ulcerative Colitis: Methotrexate's Role in Remission

Ulcerative colitis (UC), a chronic inflammatory bowel disease, presents a significant challenge for patients and healthcare providers alike. This research, like a skilled cartographer meticulously mapping a complex terrain, investigates the effectiveness of methotrexate, a medication commonly used in treating various inflammatory diseases, in inducing remission in patients with UC. The authors, like experienced explorers venturing into uncharted territory, conduct a comprehensive review of existing literature, seeking to understand methotrexate's role in managing UC and its potential benefits.

A Potential Ally in Combating UC: Methotrexate's Effectiveness in Remission

The review's findings, like a valuable resource discovered in a desolate desert, reveal that methotrexate shows promise in inducing remission in UC patients, particularly those who have not responded well to conventional therapies. The authors, like astute detectives analyzing evidence, carefully examine the available data, finding that methotrexate can be an effective treatment option for steroid-refractory and steroid-dependent UC. This discovery, like a hidden oasis offering relief and rejuvenation, provides hope for patients seeking alternative and effective treatment strategies.

Guiding Treatment Decisions: Navigating the Path to Remission

This review, like a compass guiding travelers through a complex and challenging landscape, provides valuable insights into the potential role of methotrexate in managing UC. The findings, like a roadmap revealing hidden pathways, underscore the importance of exploring alternative treatment options, particularly for patients who have not responded well to conventional therapies. By understanding the complexities of UC and its treatment, we can pave the way for more effective and personalized treatment strategies, offering hope to patients seeking a path to remission.

Dr. Camel's Conclusion

This review underscores the potential of methotrexate as a valuable treatment option for UC, particularly for patients who have not responded well to conventional therapies. The research, like a well-worn trail leading to a hidden oasis, provides valuable insights into methotrexate's role in managing UC, offering hope to patients seeking a path to remission.

Date :
  1. Date Completed 2014-09-19
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

25162749

DOI: Digital Object Identifier

PMC6486224

SNS
PICO Info
in preparation
Languages

English

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